Working…
ClinicalTrials.gov
ClinicalTrials.gov Menu

Osteoarticular Infections With Pneumococcal

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT03852784
Recruitment Status : Recruiting
First Posted : February 25, 2019
Last Update Posted : February 25, 2019
Sponsor:
Information provided by (Responsible Party):
Eugénie MABRUT, Hospices Civils de Lyon

Brief Summary:
Osteoarticular infections at pneumococcal are rare, potentially serious and remain under diagnosed. They represent 3 at 10% of the arthritis septic in the literature. 190 cases have been published of 1965 at 2003. They represent 0.3% at 0.6% of the bacteraemia at Streptococcus peumoniae.

Condition or disease Intervention/treatment
Bone and Joint Infection Other: Bone and joint infection with Streptococcus peumoniae

Layout table for study information
Study Type : Observational
Estimated Enrollment : 33 participants
Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Osteoarticular Infections With Pneumococcal
Actual Study Start Date : January 1, 2019
Estimated Primary Completion Date : March 1, 2019
Estimated Study Completion Date : April 1, 2019

Group/Cohort Intervention/treatment
Bone and joint infection with Streptococcus peumoniae
Patients having had an osteoarticular infection with Streptococcus peumoniae
Other: Bone and joint infection with Streptococcus peumoniae
description of the osteoarticular infection with Streptococcus peumoniae




Primary Outcome Measures :
  1. Description and rate of bone or joint infection with S. pneumoniae [ Time Frame: Outcome is measured at the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption ]
    Description of the type of infection due to S. pneumoniae : patients and type of implant, profile of the bacterium associated in the infection, medical and chirurgical treatment


Secondary Outcome Measures :
  1. Rate of Treatment Failure [ Time Frame: Outcome is measured at the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption ]
    Treatment failure is defined by local clinical and/or microbiological relapse; and/or need for additional surgery; death of septic origin



Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Layout table for eligibility information
Ages Eligible for Study:   18 Years to 100 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Sampling Method:   Non-Probability Sample
Study Population
patients having had a bone and joint infection with S pneumoniae, with or without device managed at the Croix-Rousse hospital
Criteria

Inclusion Criteria:

  • patients having had a bone and joint infection with S pneumoniae, with or without device.

Exclusion Criteria:

  • none

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03852784


Contacts
Layout table for location contacts
Contact: Eugenie Mabrut, CRA 04 26 73 29 38 eugenie.mabrut@chu-lyon.fr
Contact: Tristan Ferry, Md,PhD 04 26 73 29 38

Locations
Layout table for location information
France
Hospices Civils de Lyon Recruiting
Lyon, France, 69004
Contact: Eugenie Mabrut, CRA         
Sponsors and Collaborators
Hospices Civils de Lyon
Investigators
Layout table for investigator information
Study Director: Tristan Ferry, Md,PhD Hospices Civils de Lyon

Additional Information:
Layout table for additonal information
Responsible Party: Eugénie MABRUT, clinical reserach assistant, Hospices Civils de Lyon
ClinicalTrials.gov Identifier: NCT03852784     History of Changes
Other Study ID Numbers: N° en attente
First Posted: February 25, 2019    Key Record Dates
Last Update Posted: February 25, 2019
Last Verified: February 2019
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: Undecided

Layout table for additional information
Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Keywords provided by Eugénie MABRUT, Hospices Civils de Lyon:
Bone and Joint Infection
Streptococcus peumoniae
Additional relevant MeSH terms:
Layout table for MeSH terms
Infection
Communicable Diseases