Bronchoscopy in Lower Respiratory Tract Infection in Respiratory Intensive Care Unit
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|ClinicalTrials.gov Identifier: NCT03846401|
Recruitment Status : Not yet recruiting
First Posted : February 19, 2019
Last Update Posted : February 19, 2019
|Condition or disease||Intervention/treatment|
|Lower Respiratory Tract Infection||Device: fiberoptic bronchoscopy|
Show Detailed Description
|Study Type :||Observational|
|Estimated Enrollment :||100 participants|
|Official Title:||Evaluation of Role of Fiberoptic Bronchoscopy in Patients With Lower Respiratory Tract Infection in Respiratory Intensive Care Unit of Assiut University Hospital|
|Estimated Study Start Date :||January 2020|
|Estimated Primary Completion Date :||January 2021|
|Estimated Study Completion Date :||May 2021|
- Device: fiberoptic bronchoscopy
Will be performed according to British Thoracic Society guidelines 2013.
-Microbiological methods The specimen (tracheal aspirate & BAL) will be collected under aseptic conditions in a sterile container and immediately sent to the laboratory for microbiological analyses.
Samples will be apply for:
- Direct smear by Gram stain and ZeihlNelseen stain
- Samples culturedinBact/alert bottle(BioMérieux, France).
Isolation of causative organism from positive cases by:
Subculture on MacConkey , blood , chocolate agar , Sabouroud`s agar and Lowenstien Jensen media.
- Identification of isolated organism and drug sensitivity test by Automated Vitek2 Compact(BioMérieux, France).
- Multiplex PCR for detection of Respiratory viruses in lower respiratory tract
- Antimicrobial resistance pattern [ Time Frame: 1 year ]isolated organism and drug sensitivity test by Automated Vitek2 Compact(BioMérieux, France).
- pathogen identification [ Time Frame: 1 year ]by Multiplex PCR
- recovering an array of microorganisms [ Time Frame: 1 year ]by BACT/ALERT® Culture Media
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03846401
|Contact: Yara Y. Omar, MDemail@example.com|
|Study Chair:||Maha K. Ghanem, Prof||Assiut University|
|Study Director:||Hoda A. Makhlouf, Prof||Assiut University|
|Study Director:||Ali A. Hasan, ass. prof.||Assiut University|
|Study Director:||Asmaa O. Ahmed, ass. prof||Assiut University|