Hoarding Disorder Treatment With Virtual Reality (HDVR)

• ClinicalTrials.gov Identifier: NCT03828461
• Recruitment Status: Enrolling by invitation
• First Posted: February 4, 2019
• Last Update Posted: April 7, 2020
• Sponsor: Stanford University
• Collaborator: National Institute on Aging (NIA)
• Information provided by (Responsible Party): Carolyn Rodriguez, Stanford University

Study Description

Brief Summary:

This study explores whether a facilitated peer support group called Buried in Treasures (BIT) and a virtual reality decluttering practice can help individuals with clutter challenges.

Condition or disease	Intervention/treatment	Phase
Hoarding Disorder; Hoarding; Clutter	Behavioral: Facilitated group therapy with behavioral practice; 16 weeks	Not Applicable

Detailed Description:

Individuals with clutter challenges participate in Buried in Treasures Workshop (BIT) that has been shown to improve symptoms of hoarding disorder. The investigators hypothesize that adding virtual reality decluttering practice to the BIT workshop will decrease hoarding symptoms and level of clutter over time.

Study Design

• Study Type: Interventional (Clinical Trial)
• Estimated Enrollment: 20 participants
• Allocation: N/A
• Intervention Model: Single Group Assignment
• Masking: None (Open Label)
• Primary Purpose: Treatment
• Official Title: Enhancing Evidence-Based Treatment of Hoarding Disorder With Virtual Reality
• Actual Study Start Date: November 6, 2019
• Estimated Primary Completion Date: April 1, 2021
• Estimated Study Completion Date: April 1, 2022

Arms and Interventions

Arm	Intervention/treatment
Experimental: BITS + VR; Facilitated group therapy with behavioral practice; 16 weeks	Behavioral: Facilitated group therapy with behavioral practice; 16 weeks; Facilitated group therapy for hoarding disorder with behavioral practice

Outcome Measures

Primary Outcome Measures :

1. Saving Inventory-Revised (SI-R) [ Time Frame: Change from baseline at 8 weeks and 16 weeks after treatment ]

   The Saving Inventory-Revised scale (SI-R) is a 23-item questionnaire with 3 factor-analytically defined sub-scales for difficulty discarding, excessive clutter, and compulsive acquisition.

   The total score (sum of 23 items) ranges from 0 to 92. Total score higher than 41 shows significant difficulty with clutter.

   For the acquisition subscale we sum items 2 (reverse score), 9, 11, 14, 16, 18 and 21. The subscale ranges from 0 to 28 and score greater than 13 indicates difficulty with excessive acquisition.

   For the difficulty discarding subscale we sum items 4(reverse score), 6, 7, 13, 17, 19, 23. The subscale ranges from 0 to 28 and score greater than 13 indicates difficulty with discarding.

   For the clutter subscale we sum items 1, 3, 5, 8, 10, 12, 15, 20, 22. The subscale ranges from 0 to 36 and score greater than 15 indicates difficulty with accumulated clutter.

Secondary Outcome Measures :

1. Clutter Image Rating Scale [ Time Frame: Change from baseline at 8 weeks and 16 weeks after treatment ]

   Three sets of photographs, each containing nine photos of a single room with varying levels of clutter. A selection is made as to which photograph best resembles their own home.

   This scale assesses the clutter levels in the bedroom, living room and kitchen. The scale for each room ranges from 1 to 9. Clutter that reaches the level 4 indicates significant difficulty with clutter that affects the person's life.

Eligibility Criteria

• Ages Eligible for Study: 56 Years and older (Adult, Older Adult)
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Criteria

Inclusion Criteria:

1. Age greater than 55
2. Either gender and all ethno-racial groups
3. Physically healthy male or non-pregnant female.
4. Hoarding Disorder primary condition
5. Willing and able to understand and complete consent and study procedures
6. English speaking
7. Participant should have the technology to host Zoom calls

Exclusion Criteria:

1. Current or past history of bipolar, psychotic or eating disorders, substance dependence, or substance abuse in the last year.
2. Clinically at risk of suicide with Columbia Suicide Severity Rating Scale (C-SSRS) Suicidal Ideation Subscale of 4 or higher (i.e. suicidal intent without specific plan)
3. Major medical or neurological conditions that increase the risk of participation or that would prevent completing assigned behavioral practice tasks.
4. Unable or unwilling to allow study staff into home for home assessment
5. Currently at high risk for eviction
6. Animal hoarding or squalor

Contacts and Locations

Locations

United States, California

Stanford Psychiatry Department

Stanford, California, United States, 94305

Sponsors and Collaborators

Stanford University

National Institute on Aging (NIA)

Investigators

• Principal Investigator: Carolyn I Rodriguez, MD, PhD; Stanford University

More Information

Additional Information:

Rodriguez Lab Website 

Dr. Carolyn Rodriguez Faculty Page 

• Responsible Party: Carolyn Rodriguez, Assistant Professor, Stanford University
• ClinicalTrials.gov Identifier: NCT03828461
• Other Study ID Numbers: 41899; 1P30AG059307 ( U.S. NIH Grant/Contract )
• First Posted: February 4, 2019
• Last Update Posted: April 7, 2020
• Last Verified: April 2020

• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No

Keywords provided by Carolyn Rodriguez, Stanford University:

hoarding disorder; hoarding; clutter

Additional relevant MeSH terms:

Disease; Hoarding Disorder; Pathologic Processes; Obsessive-Compulsive Disorder; Anxiety Disorders; Mental Disorders