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Polarization Perception in Health and Disease. Testing a New Sight Test (TaNSiT)

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ClinicalTrials.gov Identifier: NCT03823092
Recruitment Status : Recruiting
First Posted : January 30, 2019
Last Update Posted : January 30, 2019
Sponsor:
Collaborator:
Aston University
Information provided by (Responsible Party):
Gary Misson, South Warwickshire NHS Foundation Trust

Brief Summary:
A study to assess the utility of human polarization pattern perception for the detection, diagnosis and monitoring of eye disease

Condition or disease Intervention/treatment
Cataract Age Related Macular Degeneration Pseudophakia Macular Disease Diabetic Retinopathy Retinal Disease Diagnostic Test: polarization sensitivity

  Show Detailed Description

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Study Type : Observational
Estimated Enrollment : 300 participants
Observational Model: Case-Control
Time Perspective: Cross-Sectional
Official Title: Polarization Perception in Health and Disease. Testing a New Sight Test: The TaNSiT Study
Actual Study Start Date : November 9, 2017
Estimated Primary Completion Date : April 2019
Estimated Study Completion Date : July 2019

Resource links provided by the National Library of Medicine


Group/Cohort Intervention/treatment
Normal
phakic participants with no evidence of eye disorders
Diagnostic Test: polarization sensitivity
test of polarization vision as described in Study Description

Cataract
participants with cataract
Diagnostic Test: polarization sensitivity
test of polarization vision as described in Study Description

AMD
participants with age related macular degeneration
Diagnostic Test: polarization sensitivity
test of polarization vision as described in Study Description

Pseudophakic
particpiants who have had cataract surgery with intraocular lens implant
Diagnostic Test: polarization sensitivity
test of polarization vision as described in Study Description

other macula
participants with macular ddisorders other than AMD
Diagnostic Test: polarization sensitivity
test of polarization vision as described in Study Description

DR
participants with diabetic retinopathy
Diagnostic Test: polarization sensitivity
test of polarization vision as described in Study Description




Primary Outcome Measures :
  1. polarization sensitivity [ Time Frame: 18 month ]
    determine and compare polarization sensitivity between groups



Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Patients and staff of the Eye Department of South Warwickshire NHS Trust
Criteria

Inclusion Criteria:

- willing and able to provide informed consent

Exclusion Criteria:

  • unwilling or unable to provide informed consent
  • individuals wishing to exit the study

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03823092


Contacts
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Contact: Gary P Misson, PhD FRCOphth +44 01926495321 gary.misson@swft.nhs.uk
Contact: Jo Williams +44 01926495321 jo.williams@swft.nhs.uk

Locations
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United Kingdom
South Warwickshire NHS Foundation Trust Recruiting
Warwick, Warwickshire, United Kingdom, CV37 0PZ
Contact: Gary P Misson, PhD FRCOphth    +44 01926495321    gary.misson@swft.nhs.uk   
Contact: Jo Williams    +44 01926495321    jo.williams@swft.nhs.uk   
Sub-Investigator: Stephen J Anderson, PhD FRCOptom         
Sponsors and Collaborators
South Warwickshire NHS Foundation Trust
Aston University

Publications of Results:
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Responsible Party: Gary Misson, Consultant ophthalmologist, South Warwickshire NHS Foundation Trust
ClinicalTrials.gov Identifier: NCT03823092     History of Changes
Other Study ID Numbers: 17/WA/0180
First Posted: January 30, 2019    Key Record Dates
Last Update Posted: January 30, 2019
Last Verified: January 2019
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No

Keywords provided by Gary Misson, South Warwickshire NHS Foundation Trust:
macular function
polarization perception
Haidinger's brush
vision testing
cataract
age related macular degeneration
pseudophakia
macular disease
retinal disease

Additional relevant MeSH terms:
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Macular Degeneration
Cataract
Diabetic Retinopathy
Retinal Diseases
Pseudophakia
Retinal Degeneration
Eye Diseases
Lens Diseases
Diabetic Angiopathies
Vascular Diseases
Cardiovascular Diseases
Diabetes Complications
Diabetes Mellitus
Endocrine System Diseases
Signs and Symptoms