the Efficacy of Giomer Versus Sodium Fluoride in the Treatment of Hypersensitivity
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|ClinicalTrials.gov Identifier: NCT03818945|
Recruitment Status : Recruiting
First Posted : January 28, 2019
Last Update Posted : January 28, 2019
|Condition or disease||Intervention/treatment||Phase|
|Tooth Hypersensitivity||Drug: shofu PRG barrier coat Drug: Sodium fluoride varnish||Phase 4|
The dentin hypersensitivity is characterized by short, sharp pain which can be detected by several methods. The problem is very annoying for the patients and making them seek for effective rapid treatment.
It can affect several teeth in one area of the mouth or only one specific tooth. Careful diagnosis of such condition necessitates precise differentiation of its signs and symptoms from the other causes of tooth sensitivity which may be resulted from dental caries, micro leakage, cracked tooth or fractured restoration. There are two well-known ways to reduce the discomfort of the hypersensitivity either by blocking the exposed dentinal tubules by occluding materials or use some depolarizing agents that reducing the excitability of the intra dental nerves.Most of the desensitizing agents reduces the dentin hypersensitivity by its own way and each one has different long lasting effect. But there are some drawbacks that appeared with their use. Fluoride based agents were appeared in 90's but it was clarified that their high concentration irritated the odontoblasts. Furthermore, the oxalates and potassium nitrate were introduced to treat the hypersensitivity effectively but their effects did not persist for a long period of time.
Sodium fluoride varnish is one from the most commonly used desensitizing agent and its efficacy was approved in many studies. The Giomer varnish containing surface pre-reactive glass particles (S-PRG) is a light-cured protective varnish and it was introduced to promote prolonged protection for the hypersensitive dentin.
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||104 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Double (Participant, Outcomes Assessor)|
|Official Title:||Clinical Efficacy of Giomer Versus Sodium Fluoride Varnish for Management of Hypersensitivity: Randomized Control Trail|
|Estimated Study Start Date :||March 1, 2019|
|Estimated Primary Completion Date :||June 1, 2019|
|Estimated Study Completion Date :||September 1, 2019|
|Sodium Fluoride Varnish||
Drug: Sodium fluoride varnish
5% sodium fluoride [22,600 ppm F-]
Other Name: Biofluoride 5% Fluoride varnish single use dose - Vocoo
|Active Comparator: PRG barrier Giomer||
Drug: shofu PRG barrier coat
Trilaminar structure which forms a type of stable glass ionomer allowing ion release and recharge, while protecting the glass core from the damaging effects of moisture, greatly improving long-term durability.(Na, BO3, Al, SiO3, F,Sr)
Other Name: Light cured giomer
- relieving of hypersensitivity [ Time Frame: one month ]The sensitive teeth will be assessed by two stimuli: tactile and thermal stimuli than scored according to the visual analog scale from zero to ten.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03818945
|Faculty of Dentistry||Recruiting|
|Contact: Nourane Yassin, Bachelor 01006889918 Nourane090248@miuegypt.edu.eg|
|Contact: Aya Nemtallah, Master Degree 01006682419 email@example.com|