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Assessment Of Anterior Chamber Configuration Changes After Phacoemulsification With Swept-Source Optical Coherence Tomography

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ClinicalTrials.gov Identifier: NCT03779542
Recruitment Status : Recruiting
First Posted : December 18, 2018
Last Update Posted : December 18, 2018
Sponsor:
Information provided by (Responsible Party):
Yune Zhao, Wenzhou Medical University

Brief Summary:
To assess the changes of anterior chamber angle in patients with shallow anterior chamber and normal anterior chamber after phacoemulsification and intraocular lens implantation (IOL) using anterior segment swept-source optical coherence tomography (AS-SS-OCT).To observe the 60 eyes of 60 patients in our study.

Condition or disease Intervention/treatment
Anterior Chamber Parameters Phacoemulsification Anterior Segment Swept-source Optical Coherence Tomography Procedure: cataract surgery

Detailed Description:
This is a prospective case-control study; 60 eyes of 60 patients who underwent cataract surgery. Based on anterior chamber depth (ACD) and gonioscopy findings, the eyes are classified into two groups, shallow anterior chamber group (30 eyes) and narrow anterior chamber group (30 eyes). AS-SS-OCT was used to measure ACD and angle parameters (angle opening distance(AOD), angle recess area(ARA), trabecular iris space area(TISA), and trabecular iris angle (TIA). Serial changes in each group were measured before and 3 months after phacoemulsification and IOL, and the differences between the two groups were compared.

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Study Type : Observational
Estimated Enrollment : 60 participants
Observational Model: Case-Control
Time Perspective: Prospective
Official Title: Assessment Of Anterior Chamber Configuration Changes After Phacoemulsification With Swept-Source Optical Coherence Tomography
Actual Study Start Date : January 1, 2018
Actual Primary Completion Date : June 30, 2018
Estimated Study Completion Date : June 2019

Group/Cohort Intervention/treatment
open-angle group
ACD > 2.68 measured by the swept source AS-OCT and angle > Shaffer 2 in four quadrants under gonioscope
Procedure: cataract surgery
phacoemulsification and intraocular lens implantation

narrow-angle group
ACD≤2.68 measured by the swept source AS-OCT and angle≤Shaffer 2 in four quadrants under gonioscope
Procedure: cataract surgery
phacoemulsification and intraocular lens implantation




Primary Outcome Measures :
  1. anterior chamber depth [ Time Frame: 1 year ]


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Ages Eligible for Study:   40 Years to 85 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
patients who underwent cataract surgery
Criteria

Inclusion Criteria: patients who underwent cataract surgery -

Exclusion Criteria:patients with mild cataracts do not require surgery

-


Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03779542


Contacts
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Contact: Man Hu, MD +86-0571-88185666 64344308@qq.com

Locations
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China, Zhejiang
Eye Hospital of Wenzhou Medical College Recruiting
Wenzhou, Zhejiang, China, 325027
Contact: Man Hu, MD    13738069080    64344308@qq.com   
Sponsors and Collaborators
Yune Zhao

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Responsible Party: Yune Zhao, Director, Wenzhou Medical University
ClinicalTrials.gov Identifier: NCT03779542     History of Changes
Other Study ID Numbers: HM-AOD-HZ
First Posted: December 18, 2018    Key Record Dates
Last Update Posted: December 18, 2018
Last Verified: December 2018

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Keywords provided by Yune Zhao, Wenzhou Medical University:
anterior chamber parameters
phacoemulsification
anterior segment swept-source optical coherence tomography