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Trial record 2 of 17 for:    chondrosarcoma | Recruiting, Not yet recruiting, Available Studies

Synovial Chondrosarcoma: a Single Institution Experience

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT03776942
Recruitment Status : Recruiting
First Posted : December 17, 2018
Last Update Posted : December 17, 2018
Sponsor:
Information provided by (Responsible Party):
Istituto Ortopedico Rizzoli

Brief Summary:
single institution cases series review of histological, radiological and clinical data

Condition or disease
Synovial Chondrosarcoma

Detailed Description:
single institution cases series review of histological, radiological and clinical data. Investigators will retrieve from the archives of the Rizzoli institute all the cases with a histological diagnosis of synovial chondrosarcoma.

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Study Type : Observational
Estimated Enrollment : 10 participants
Observational Model: Case-Only
Time Perspective: Retrospective
Official Title: Synovial Chondrosarcoma: a Single Institution Experience
Actual Study Start Date : August 1, 2018
Estimated Primary Completion Date : August 1, 2019
Estimated Study Completion Date : August 1, 2019

Resource links provided by the National Library of Medicine





Primary Outcome Measures :
  1. selection and review of 10 cases of Synovial Chondrosarcoma [ Time Frame: baseline (Day0) ]
    IDH1 and IDH2 analysis will be performed in order to better understand tumor characteristics and to identify the best therapeutic approach.


Biospecimen Retention:   Samples Without DNA
tumor samples will be analysed by Dr. Dei Tos


Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Sampling Method:   Non-Probability Sample
Study Population
Male and Female ≥ 18 years with diagnosis of synovial chondrosarcoma with histological slides/formalin-fixed paraffin-embedded tissue tumor blocks from archive available to perform the histology analysis
Criteria

Inclusion Criteria:

  • Male and female patients treated at Rizzoli Institute from 01 January 1982 to 31 December 2017
  • Diagnosis of synovial chondrosarcoma
  • Age ≥ 18 years
  • Histological slides / formalin-fixed paraffin-embedded tissue tumor (FFPE) blocks from archive available to perform the histology analysis
  • Written informed consent prior to any study-specific analysis and/or data collection

Exclusion Criteria:

  • Patients with histological diagnosis different from synovial chondrosarcoma

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03776942


Contacts
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Contact: Marco Gambarotti +39/051.63.66 ext 652 marco.gambarotti@ior.it

Locations
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Italy
IRCC Rizzoli Orthopedic Institute Recruiting
Bologna, Italy, 40136
Contact: Marco Gambarotti, MD    +390516366 ext 650    marco.gambarotti@ior.it   
Sponsors and Collaborators
Istituto Ortopedico Rizzoli
  Study Documents (Full-Text)

Documents provided by Istituto Ortopedico Rizzoli:
Study Protocol  [PDF] May 16, 2018


Publications of Results:
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Responsible Party: Istituto Ortopedico Rizzoli
ClinicalTrials.gov Identifier: NCT03776942     History of Changes
Other Study ID Numbers: SynoChondroS
First Posted: December 17, 2018    Key Record Dates
Last Update Posted: December 17, 2018
Last Verified: December 2018

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No

Additional relevant MeSH terms:
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Chondrosarcoma
Neoplasms, Connective Tissue
Neoplasms, Connective and Soft Tissue
Neoplasms by Histologic Type
Neoplasms
Sarcoma