HPV Message Testing and Social Media Campaign

• ClinicalTrials.gov Identifier: NCT03747302
• Recruitment Status: Enrolling by invitation
• First Posted: November 20, 2018
• Last Update Posted: August 14, 2019
• Sponsor: Dartmouth-Hitchcock Medical Center
• Collaborators: National Cancer Institute (NCI); Norris Cotton Cancer Center
• Information provided by (Responsible Party): Ardis Olson, MD, Trustees of Dartmouth College

Study Description

Brief Summary:

This project involves a social media campaign to increase parent's knowledge and acceptance of the HPV (human papillomavirus) vaccine. The current vaccine protects against nine types of HPV, including seven that are known to cause cancer. The Centers for Disease Control and Prevention (CDC) estimates that the current HPV vaccine could prevent 90% of cancer cases caused by HPV, including cases of cervical cancer, oropharyngeal (mouth and throat) cancer, anal cancer, and others. About 150 and 104 cases of HPV-associated cancers are diagnosed each year in New Hampshire and Vermont, respectively—many of which could be prevented through vaccination. Currently, only 49.8% of New Hampshire adolescents and 44.3% of Vermont adolescents were not up-to-date for HPV vaccination as of 2016. This social media campaign is testing a set of campaign messages with parents locally and nationally to see which messages are most effective in improving their knowledge and acceptance of the vaccine. A study survey link will monitor the number of people reached and will measure parental intention to get their children vaccinated against HPV.

Condition or disease	Intervention/treatment	Phase
Vaccine; Human Papilloma Virus	Other: Social Media Message about HPV and HPV vaccine; Other: Social media message about risk of electronic cigarettes.	Not Applicable

Study Design

• Study Type: Interventional (Clinical Trial)
• Estimated Enrollment: 1200 participants
• Allocation: Randomized
• Intervention Model: Parallel Assignment
• Masking: Single (Participant)
• Masking Description: Participants are not aware of which arm of social messaging they are receiving and whether they are receiving the control message or not
• Primary Purpose: Health Services Research
• Official Title: HPV Message Testing and Social Media Campaign
• Actual Study Start Date: December 12, 2018
• Estimated Primary Completion Date: December 2019
• Estimated Study Completion Date: December 2019

Arms and Interventions

Arm	Intervention/treatment
Experimental: HPV Messaging; Subjects are randomized to receive one of five messages on one of the four themes about HPV vaccination.	Other: Social Media Message about HPV and HPV vaccine; Messages educate parents with facts about HPV vaccination.
Control Message; Subjects are randomized to receive one of five messages about electronic cigarettes.	Other: Social media message about risk of electronic cigarettes.; Messages educate parents with facts about electronic cigarettes. This is an attention control group without outcomes obtained.

Outcome Measures

Primary Outcome Measures :

1. Changes in intention to vaccinate their child with HPV vaccine [ Time Frame: pre test immediately before viewing message and post test immediately after viewing message. Approximately one hour. ]
   Pre and Post surveys of participants viewing a specific social message

Eligibility Criteria

• Ages Eligible for Study: Child, Adult, Older Adult
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: Yes

Criteria

Inclusion Criteria:

• parents of children 9-14 years old

Exclusion Criteria:

• non-parents

Contacts and Locations

Locations

United States, New Hampshire

Dartmouth-Hitchcock Medical Center

Lebanon, New Hampshire, United States, 03756

Sponsors and Collaborators

Dartmouth-Hitchcock Medical Center

National Cancer Institute (NCI)

Norris Cotton Cancer Center

Investigators

• Principal Investigator: Ardis L Olson, MD; Trustees of Dartmouth College
• Principal Investigator: Sun Jung Kim, PhD; Massey Cancer Center

More Information

Additional Information:

HPV cancer diagnosis rates  HPV cancer diagnosis rates  HPV vaccination rates 

• Responsible Party: Ardis Olson, MD, Physician, Professor of Pediatrics, Trustees of Dartmouth College
• ClinicalTrials.gov Identifier: NCT03747302 History of Changes
• Other Study ID Numbers: D18180; 3P30CA023108-38S4 ( U.S. NIH Grant/Contract )
• First Posted: November 20, 2018
• Last Update Posted: August 14, 2019
• Last Verified: August 2019

• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No

Keywords provided by Ardis Olson, MD, Trustees of Dartmouth College:

Adolescence; Attitudes; Parents; Vaccination

Additional relevant MeSH terms:

Papilloma; Neoplasms, Squamous Cell; Neoplasms, Glandular and Epithelial; Neoplasms by Histologic Type; Neoplasms; Vaccines; Immunologic Factors; Physiological Effects of Drugs