Try the modernized beta website. Learn more about the modernization effort.
Working… Menu

Cone Beam Computed Tomography Versus Intraoral Digital Radiography in Detection and Measurements of Simulated Periodontal Bone Defects

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT03729843
Recruitment Status : Unknown
Verified November 2018 by Marwa Mohamed Ali, Cairo University.
Recruitment status was:  Not yet recruiting
First Posted : November 5, 2018
Last Update Posted : November 6, 2018
Information provided by (Responsible Party):
Marwa Mohamed Ali, Cairo University

Brief Summary:

The selection of a regenerative approach is primarily based on the configuration of the intrabony defect and esthetic risk of treatment. Accurate diagnosis of periodontal bone defects, such as vertical bone defects or furcation involvements, is a challenge for dental clinicians. A deficiency in comprehensive diagnosis may result in: 1) compromised prognosis of teeth; 2) changes in treatment plan; 3) unnecessary treatment; 4) longer treatment time; and 5) unanticipated treatment costs.

Thus, it is very important to have access to accurate diagnostic tools that can aid clinicians in cultivating an appropriate treatment choice. Periodontal assessments utilizing both clinical and radiographic examinations allow for the establishment of an accurate diagnosis as well as subsequent treatment choices.

Radiography plays an important role in periodontal diagnosis mainly because radiographs can reveal the amount and type of damage caused to the alveolar bone.

Digital imaging technique has created challenging opportunities for dental radiographic diagnosis. Digora was the first digital system for dental radiography based on a photostimulable phosphor technology.

E9ickholz et al. at 1999 compared linear measurements of interproximal bone loss on digitized radiographic images after application of different filters to the gold standard of intrasurgical measurements they concluded that all radiographic assessments on the digitized images came close to the intasurgical gold standard.

2D technologies do not allow for measurement of the bucco-lingual (B-L) width of the defect. Only the vertical height and the mesio-distal (M-D) width of the defect can be measured with 2D images.

Use of 3D volumetric images and 2D images in artificial bone defects have shown that CBCT has a sensitivity of 80% to 100% in detection and classification of bone defects, while intraoral radiographs present a sensitivity of 63% to 67%.

When compared with periapical and panoramic images, the CBCT has also shown an absence of distortion and overlapping, and the dimensions of the images that it presents were compatible with the actual size of the individual.

A few studies have been published comparing CBCT with digital radiography for the detection and measurements of periodontal bone defects.

Condition or disease Intervention/treatment
Periodontal Bone Defects Will be Detected and Measured by 2 Techniques CBCT and Intraoral Digital Radiography to Compare the Accuracy of These Techniques Radiation: CBCT and intraoral digital radiography

Show Show detailed description

Layout table for study information
Study Type : Observational
Estimated Enrollment : 15 participants
Observational Model: Other
Time Perspective: Other
Official Title: Cone Beam Computed Tomography Versus Intraoral Digital Radiography in Detection and Measurements of Simulated Periodontal Bone Defects Diagnostic Accuracy Study
Estimated Study Start Date : November 10, 2018
Estimated Primary Completion Date : November 10, 2019
Estimated Study Completion Date : November 10, 2020

Resource links provided by the National Library of Medicine

MedlinePlus related topics: X-Rays
Drug Information available for: X-Rays

Group/Cohort Intervention/treatment
CBCT and intraoral digital radiography
simulated bone defects will be detected and measured by 2 techniques using CBCT and using intraoral digital radiography and the all measurements will be compared with the gold standard real measurements on the dry jaws
Radiation: CBCT and intraoral digital radiography
Simulated periodontal bone defects will be measured by 2 techniques: group I detected and measured using CBCT and group II intraoral digital radiography and all the measurements will be compared with the gold standard real measurements on the dry jaws

Primary Outcome Measures :
  1. CBCT and Intraoral Digital Radiography [ Time Frame: 24 months ]
    Detection and measuring of artificially prepared periodontal bone defects.

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Layout table for eligibility information
Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patially or fully dentate dry jaws that match with the inclusion and exclusion criteria.

Inclusion Criteria:

  • • The selected dry jaws should be intact with no mechanical damage (chips, cracks, or fractures in the alveolar process).

    • The teeth will be naturally attached to human jaws.
    • The study samples will not identified by age or gender group.

Exclusion Criteria:

  • • teeth with metallic restorations to avoid artifacts generation on CBCT scanning.

    • Teeth with anomalies and fractures.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT03729843

Layout table for location contacts
Contact: marwa m ali, master 00201091608076

Sponsors and Collaborators
Marwa Mohamed Ali
Layout table for investigator information
Study Chair: Hossam Kandil, Professor Cairo University
Layout table for additonal information
Responsible Party: Marwa Mohamed Ali, Lecturer Assistant of Oral Radiology Department, Cairo University Identifier: NCT03729843    
Other Study ID Numbers: HPHH
First Posted: November 5, 2018    Key Record Dates
Last Update Posted: November 6, 2018
Last Verified: November 2018

Layout table for additional information
Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No