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Trial record 3 of 5 for:    10987628 [PUBMED-IDS]

Aerobic Interval Training v/s Resistance Interval Training On Ejection Fraction In Stable Post MI Patients

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ClinicalTrials.gov Identifier: NCT03708484
Recruitment Status : Completed
First Posted : October 17, 2018
Last Update Posted : August 9, 2019
Sponsor:
Information provided by (Responsible Party):
Riphah International University

Brief Summary:
Randomized controlled trial (single blinded) study was conducted on 26 stable Post MI patients according to inclusion and exclusion criteria aged 35 to 65 years. Study was conducted in Rawalpindi Institute of cardiology and Pakistan Railway Hospital from July 2016 ---- December 2016.Participants was randomly allocated in control or experimental group by lottery Method. Informed consent was signed by each participant prior to enrolment. Patients in both group received standard treatment that is Aerobic Interval training whereas patients in interventional group received additional Resistance training. Post echocardiography and lipid profile was done to assess the effect of intervention on ejection fraction, cholesterol and triglycerides. The standard questionnaire Mac New QLMI was used to assess quality of life. The data was analyzed on SPSS 21

Condition or disease Intervention/treatment Phase
Myocardial Infarction Other: Aerobic Interval Training Other: Aerobic + Resistive Interval Training Not Applicable

  Show Detailed Description

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 26 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Investigator)
Primary Purpose: Other
Official Title: Effect of Aerobic Interval Training Versus Resistance Interval Training on Ejection Fraction in Post Stable Myocardial Infarction Patients
Actual Study Start Date : July 1, 2016
Actual Primary Completion Date : December 20, 2016
Actual Study Completion Date : December 25, 2016

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Heart Attack

Arm Intervention/treatment
Active Comparator: Aerobic Interval Training
Aerobic Interval Training is active comparator
Other: Aerobic Interval Training

Aerobic Interval Training Patients in this group will perform 6 minutes of cycling followed by 3 minutes of pause and again 6 minutes of cycling followed by 3 minutes of pause and finally 6 minutes of treadmill followed by 3 minutes of rest.

both groups will perform cool down exercises that include again breathing exercises, stretching and active exercises.


Experimental: Aerobic + Resistive Interval Training
Aerobic + Resistive Interval Training is experimental
Other: Aerobic + Resistive Interval Training

Aerobic + Resistive Interval Training Patients in this group; first set will perform 3 minute of cycling ,1 set of hand grippers 1.5 to 2.5 lbs (10 to 12 reps) and 1 set of biceps resistive exercises 1 Kg to 3 kg (10 to 12 reps) followed by 3minute of pause. In second set patient will perform 3 minutes of stationary cycling , 1 set of quadriceps resistive exercises 1 to 3 Kg (10 to 12 reps) again followed by 3 minutes of pause and in third set patient will perform 3 minutes of treadmill walk at 1.5 to 4 speed, and 1 set of standing ankle pumps (10 to 12 reps).

both groups will perform cool down exercises that include again breathing exercises, stretching and active exercises.





Primary Outcome Measures :
  1. Ejection Fraction [ Time Frame: 6 weeks ]
    Change from baseline Ejection fraction


Secondary Outcome Measures :
  1. MACNEW QLMI [ Time Frame: 6 weeks ]

    change from Baseline MACNEW QLMI is a self-administered heart disease-specific health-related quality of life [HRQL] instrument. The MacNew is designed to evaluate the impact of treatment, including cardiac rehabilitation, and has been shown to be valid, reliable and responsive, is simple to administer and well-accepted by patients, and normative data are available for patients with myocardial infarction, angina pectoris, and heart failure.

    The Mac New has total of 27 items with three major categories. 14 item emotional function Domain scale, 13 item physical limitations domain scale and 13 item social function domain scale. Scoring of Mac New is simple and easy. Minimum score is 1 that is poor and maximum is 7 that are high score. Missing responses are not scored. Each category is calculated as average of responses in that category.


  2. Lipid profile [ Time Frame: 6 weeks ]
    change from baseline (Lipid profile)



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Ages Eligible for Study:   35 Years to 70 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Patient who experienced just 1 episode of MI
  • Stable post MI patients after 6 weeks of MI episode
  • Patient who remained asymptomatic for first 3 minutes of ETT

Exclusion Criteria:

  • Poor LV ejection fraction below 35 % was excluded
  • Lung diseases ( lung function test moderate and severe intensity )
  • Unstable MI patients
  • Those who had undergone any cardiac surgery
  • Patients with Post MI Arrhythmias were excluded

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03708484


Locations
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Pakistan
Riphah International University
Islamabad, Pakistan, 44000
Sponsors and Collaborators
Riphah International University
Investigators
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Principal Investigator: Imran Amjad, PHD Riphah International University
  Study Documents (Full-Text)

Documents provided by Riphah International University:
Informed Consent Form  [PDF] July 15, 2016


Publications:

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Responsible Party: Riphah International University
ClinicalTrials.gov Identifier: NCT03708484     History of Changes
Other Study ID Numbers: RiphahIU Hania Farheen
First Posted: October 17, 2018    Key Record Dates
Last Update Posted: August 9, 2019
Last Verified: August 2019
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

Keywords provided by Riphah International University:
Aerobic Interval training
Ejection Fraction
Myocardial Infarction
Resistive Interval Training

Additional relevant MeSH terms:
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Infarction
Myocardial Infarction
Ischemia
Pathologic Processes
Necrosis
Myocardial Ischemia
Heart Diseases
Cardiovascular Diseases
Vascular Diseases