Pentafecta Outcomes After Robot-assisted Laparoscopic Radical Prostatectomy
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Robot-assisted laparoscopic radical prostatectomy (RALRP) is a surgical technique for the treatment of prostate cancer. The aim of this study was to report our initial experience with RALRP, by applying the concept of pentafecta. Pentafecta consists of the five main outcomes in the postoperative period of RALRP: erectile dysfunction, urinary incontinence, postoperative complications, surgical margins and biochemical failure.
Condition or disease
Prostate CancerErectile DysfunctionComplication of Surgical ProcedureUrinary Incontinence
This study will describe a initial experience in RALRP in Brazilian University Hospital. The follow-up of patients was performed as an examination at the medical consultation every three months. Complications were categorized according to the Clavien classification system. Biochemical failure was established by PSA level. Continence was defined as patients who remain dry and who do not require any kind of protection in their everyday activities. Sexual potency was defined as the ability to get and keep an erection for long enough to have satisfying sexual relations with or without the use of type-5 phosphodiesterase inhibitors (PDE-5) and a Sexual Health Inventory for Men (SHIM) score greater or equal to 21. Positive surgical margin is defined as the presence of neoplastic glands in direct contact with the ink on the surface of the piece, with no interposed connective tissue.
Sexual Health Inventory for Men (SHIM) score greater or equal to 21.
Secondary Outcome Measures :
Urinary Continence [ Time Frame: 6 months ]
Continence was defined as patients who remain dry and who do not require any kind of protection.Patients will be questioned in the postoperative consultations if there is a need to use some protection.
Surgical Complication [ Time Frame: 30 days ]
Complications were categorized according to the Clavien classification system.
Biochemical Failure [ Time Frame: 6 month ]
Biochemical failure was established by PSA level grater or equal to 0,2 ng/ml.
Surgical Margin [ Time Frame: 15 days ]
It is defined as the presence of neoplastic glands in direct contact with the ink on the surface of the piece.
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Layout table for eligibility information
Ages Eligible for Study:
40 Years to 80 Years (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Patients between 40 and 75 diagnosed with localized prostate cancer submitted to robot-assisted laparoscopic radical prostatectomy.
• patients diagnosed with localized Prostate Adenocarcinoma submitted to surgical treatment with Robot-assisted laparoscopic radical prostatectomy
patients undergoing other treatments for adenocarcinoma of the prostate