Effect of Anesthetic Agents on Optic Nerve Sheath Diameter
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|ClinicalTrials.gov Identifier: NCT03701529|
Recruitment Status : Recruiting
First Posted : October 10, 2018
Last Update Posted : January 7, 2019
|Condition or disease||Intervention/treatment||Phase|
|Uterus Myoma Uterine Cancer||Drug: Sevoflurane Drug: Propofol||Not Applicable|
Anesthetic agents (propofol and sevoflurane)have different effect on intracranial pressure. Sevoflurane when used over 0.5 minimum alveolar concentration, dilates intracranial vasculature and increases intracranial pressure. On the other hand, propofol decreases intracranial blood pressure and intracranial pressure is maintained or decreases.
Optic nerve sheath diameter is a feasible diagnostic tool in evaluating intracranial pressure. Female patients undergoing robot-assisted laparoscopic hysterectomy or myomectomy are evaluated.
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||42 participants|
|Intervention Model:||Parallel Assignment|
|Primary Purpose:||Supportive Care|
|Official Title:||Effect of Anesthetic Agents (Propofol, Sevoflurane) on Optic Nerve Sheath Diameter(ONSD) in Patients Undergoing Robot-assisted Laparoscopic Gynecology Surgery|
|Actual Study Start Date :||October 15, 2018|
|Estimated Primary Completion Date :||June 1, 2019|
|Estimated Study Completion Date :||December 1, 2019|
1.5-2.5 vol% of sevoflurane is used for maintenance of anesthesia.
1.5-2.5 vol % sevoflurane is used for maintenance of anesthesia.
Other Name: sevoflurane anesthesia
Active Comparator: Propofol
2-5 mcg/ml of propofol is used continuously for maintenance of anesthesia using target-controlled infusion system.
2-5 mcg/ml of propofol is used for maintenance of anesthesia.
Other Name: propofol anesthesia
- difference of optic nerve sheath diameter [ Time Frame: During the operation. ]optic nerve sheath diameter is measured using sonographic probe. (10 minutes after induction of anesthesia/ 5 minutes after pneumoperitoneum and trendelenburg position / 20 minutes after pneumoperitoneum and trendelenburg position / 40 minutes after pneumoperitoneum and trendelenburg position / skin closure)
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03701529
|Contact: Jun In-Jung, email@example.com|
|Korea, Republic of|
|Kangnam Sungshim Hospital||Recruiting|
|Seoul, Korea, Republic of|
|Contact: Jun , Fellow|
|Study Chair:||Choi Eun-Mi, Professor||Kangnam Sungshim Hospital|