Outflow Reconstruction in Right Lobe Living Donor Liver Transplantation
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|ClinicalTrials.gov Identifier: NCT03666689|
Recruitment Status : Not yet recruiting
First Posted : September 12, 2018
Last Update Posted : September 12, 2018
Modified Right Lobe Graft(MRLG) is one of the most common used graft in liver transplantation .Anterior sector of allograft in MRLG usually congested to decrease this congestion tributaries of middle hepatic vein should be drained to inferior vena cava .
There are too many techniques available for this drainage using either cryopreserved or synthetic graft for vascular anastomosis .In this study we will compare between two different technique using ringed synthetic polytetrafluoroethylene (PTFE) graft to assess outflow adequacy in both technique.
|Condition or disease||Intervention/treatment|
|Liver Transplant||Procedure: surgical technique|
|Study Type :||Observational|
|Estimated Enrollment :||50 participants|
|Official Title:||Outflow Reconstruction in Right Lobe Living Donor Liver Transplantation: Middle Hepatic Vein Reconstruction Versus Separate Tributaries to Inferior Vena Cava Anastomosis|
|Estimated Study Start Date :||October 1, 2018|
|Estimated Primary Completion Date :||October 2020|
|Estimated Study Completion Date :||May 2021|
Both ends of middle hepatic vein tributaries V8 and/or V5 of modified right lobe graft will be anastomosed to side of a single synthetic graft which will be anastomosed to recipient's middle/left hepatic vein orifice.
Procedure: surgical technique
Separate tributaries reconstruction
End of V8 middle hepatic vein tributary of modified right lobe graft; if present, will be anastomosed to end of a synthetic graft which will be anastomosed to recipient's middle/left hepatic vein orifice, and end of V5; if present; will be anastomosed to end of a synthetic graft which will be anastomosed to recipient's Inferior Vena Cava directly.
Procedure: surgical technique
- Outflow adequacy of liver graft within the first 6 month post transplant [ Time Frame: 6 month ]Outflow adequacy of the graft will be assessed intraoperatively by the presence of the congestion and the color of the graft and Doppler ultrasound will be done after vascular reconstruction and before closure of anterior abdominal wall. Outflow adequacy will be assessed postoperatively by Doppler ultrasound once per day for the first 5 days, then once per week for 4 weeks then 2,3,and 6 months. Computed tomography (CT) scan will be done in the 6 postoperative month
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Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03666689
|Contact: Ahmed Abdalla, firstname.lastname@example.org|