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|ClinicalTrials.gov Identifier: NCT03640130|
Recruitment Status : Enrolling by invitation
First Posted : August 21, 2018
Last Update Posted : November 14, 2018
|Condition or disease||Intervention/treatment||Phase|
|Central Visual Impairment||Behavioral: Gaze-contingent text enhancement||Not Applicable|
Participants will view paragraphs of multiple sentences of text with their central vision blocked computationally with a "simulated scotoma." Participants will be free to move their eyes around the page of text at a comfortable rate. The three outcomes described elsewhere will be evaluated.
In different blocks, text will contain one or more of several dynamic assistive manipulations that are hypothesized to enhance reading: 1) inverting the text at a given position, with instructions for the participant to attend to that location, which simulates a "surrogate fovea" of a patient with central vision loss. 2) horizontally expanding text to alleviate within-word crowding. 3) highlighting the next word with a visible indicator to encourage proper eye movements.
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||6 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Factors Limiting Peripheral Reading|
|Actual Study Start Date :||November 1, 2018|
|Estimated Primary Completion Date :||March 1, 2019|
|Estimated Study Completion Date :||March 1, 2019|
Experimental: Single Arm
Each participant will participate in several blocks (randomized order), to evaluate performance with and without behavioral gaze-contingent text enhancements.
Behavioral: Gaze-contingent text enhancement
In different testing blocks, the efficacy of the different enhancements will be evaluated, such as inverting the text in a gaze-contingent inverted "spotlight."
- Reading speed [ Time Frame: From enrollment to completion of testing (<2 weeks) ]Average time/word it takes to read a paragraph of text.
- Reading accuracy [ Time Frame: From enrollment to completion of testing (<2 weeks) ]Ability to correctly answer comprehension questions or orally read words
- Efficiency of eye movement [ Time Frame: From enrollment to completion of testing (<2 weeks) ]Ability to move the eyes systematically from word to word
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03640130
|United States, Texas|
|University of Houston, College of Optometry|
|Houston, Texas, United States, 77204|