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Peripheral Reading

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT03640130
Recruitment Status : Enrolling by invitation
First Posted : August 21, 2018
Last Update Posted : November 14, 2018
Sponsor:
Information provided by (Responsible Party):
Daniel R. Coates, University of Houston

Brief Summary:
The purpose of this study is to evaluate reading performance in the visual periphery by simulating central vision loss using a computer-controlled gaze-contingent display with an eye tracker. Participants will read a page of text at a comfortable rate. Several manipulations hypothesized to improve reading will be tested, such as an inverted-text "spotlight" of a single word that follows the participant's gaze.

Condition or disease Intervention/treatment Phase
Central Visual Impairment Behavioral: Gaze-contingent text enhancement Not Applicable

Detailed Description:

Participants will view paragraphs of multiple sentences of text with their central vision blocked computationally with a "simulated scotoma." Participants will be free to move their eyes around the page of text at a comfortable rate. The three outcomes described elsewhere will be evaluated.

In different blocks, text will contain one or more of several dynamic assistive manipulations that are hypothesized to enhance reading: 1) inverting the text at a given position, with instructions for the participant to attend to that location, which simulates a "surrogate fovea" of a patient with central vision loss. 2) horizontally expanding text to alleviate within-word crowding. 3) highlighting the next word with a visible indicator to encourage proper eye movements.

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Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 6 participants
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Other
Official Title: Factors Limiting Peripheral Reading
Actual Study Start Date : November 1, 2018
Estimated Primary Completion Date : March 1, 2019
Estimated Study Completion Date : March 1, 2019

Arm Intervention/treatment
Experimental: Single Arm
Each participant will participate in several blocks (randomized order), to evaluate performance with and without behavioral gaze-contingent text enhancements.
Behavioral: Gaze-contingent text enhancement
In different testing blocks, the efficacy of the different enhancements will be evaluated, such as inverting the text in a gaze-contingent inverted "spotlight."




Primary Outcome Measures :
  1. Reading speed [ Time Frame: From enrollment to completion of testing (<2 weeks) ]
    Average time/word it takes to read a paragraph of text.

  2. Reading accuracy [ Time Frame: From enrollment to completion of testing (<2 weeks) ]
    Ability to correctly answer comprehension questions or orally read words

  3. Efficiency of eye movement [ Time Frame: From enrollment to completion of testing (<2 weeks) ]
    Ability to move the eyes systematically from word to word



Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Normal vision
  • English language

Exclusion Criteria:

  • Less than 20/20 vision in either eye
  • Abnormalities which affect vision (amblyopia, keratoconus, etc.)
  • Ortho-K lenses

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03640130


Locations
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United States, Texas
University of Houston, College of Optometry
Houston, Texas, United States, 77204
Sponsors and Collaborators
University of Houston

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Responsible Party: Daniel R. Coates, Assistant Professor, University of Houston
ClinicalTrials.gov Identifier: NCT03640130    
Other Study ID Numbers: STUDY00001096
First Posted: August 21, 2018    Key Record Dates
Last Update Posted: November 14, 2018
Last Verified: November 2018
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: Undecided
Plan Description: To conform with open science directives, will likely post the de-identified behavioral data on a public server.

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Additional relevant MeSH terms:
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Vision Disorders
Vision, Low
Sensation Disorders
Neurologic Manifestations
Nervous System Diseases
Eye Diseases
Signs and Symptoms