Non Invasive Ventilation in Bronchiolitis
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|ClinicalTrials.gov Identifier: NCT03619499|
Recruitment Status : Not yet recruiting
First Posted : August 8, 2018
Last Update Posted : August 8, 2018
|Condition or disease||Intervention/treatment||Phase|
|Non Invasive Ventilation||Device: non invasive ventilation||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||104 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Official Title:||Non Invasive Ventilation Versus Invasive Ventilation in Management of Bronchiolitis|
|Estimated Study Start Date :||October 1, 2018|
|Estimated Primary Completion Date :||October 1, 2019|
|Estimated Study Completion Date :||October 1, 2021|
Experimental: non invasive
infants who fulfill criteria of severe bronchiolitis will be connected to non invasive ventilation
Device: non invasive ventilation
patients who will fulfill the criteria of severe bronchiolitis will be connected to non invasive ventilation including continuous positive airway pressure via nasal prongs or nasal mask. Mode of ventilation, inspired oxygen levels, oxygen saturation, respiratory rate, and blood gas values from arterial samples prior to and after 2 and 4 hrs of ventilation or nearest time, will be documented.
No Intervention: invasive
infants who were connected to invasive mechanical ventilation
- decrease risk of respiratory failure [ Time Frame: 2 days ]in the form of ( pulse oximetry less than 94⁒, pao2 less than 60mmHg, paco2 more than 84mmHg ) while on NIV that lead to connection to invasive mechanical ventilation.
- decrease length of hospital stay [ Time Frame: 7 days ]by prevention of ventilation acquired pneumonia and barotrauma that occur from use of invasive ventilation.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03619499
|Contact: azza el email@example.com|
|Contact: Ismail Lotfy||01063398967||Ismail231@aun.edu.eg|