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Trial record 41 of 57 for:    Recruiting, Not yet recruiting, Available Studies | Arthroscopy

Arthroscopic Treatment of Resistant Cases of Patellofemoral Pain

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ClinicalTrials.gov Identifier: NCT03615976
Recruitment Status : Not yet recruiting
First Posted : August 6, 2018
Last Update Posted : August 6, 2018
Sponsor:
Information provided by (Responsible Party):
muhammad kamel muhammad sayed, Assiut University

Brief Summary:

This procedure will be applied to all patient with P.F.O.A who received conservative and physical therapy treatment that was ultimately unsuccessful and the clinical manifestations still present which includes recurrent swelling and pain in the knee joint aggravated by ascending/descending stairs, squatting down, or standing up, Positive patellar grinding tests, pain mainly located at patellar edges, varying degrees of quadriceps femoris atrophy and a sense of joint friction during activities Knee‑joint X‑ray showed that the space between the patellofemoral joint was narrowed, and osteophytosis was present These patients will be treated by arthroscopy (circumpatellar denervation, partial and lateral patellar facetectomy) then compare between pre and post-operative results in pain reduction, improving knee joint function, quality of life by using 2 knee scores

  1. Scoring of patellofemoral disorders( Kujala) score
  2. Knee Injury and Osteoarthritis Outcome Score (KOOS)

followed by an average follow up to 6 months.


Condition or disease Intervention/treatment Phase
Anterior Knee Pain Syndrome Procedure: arthroscopic circumpatellar denervation with or without lat. Patellar facetectomy Not Applicable

  Show Detailed Description

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Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 50 participants
Intervention Model: Single Group Assignment
Intervention Model Description: It is prospective case series study Patients with isolated patellofemoral pain will be treated with arthroscopy and then Compare between pre and post-operative results in pain reduction, improving knee joint function, quality of life, and deferring arthritic progression.
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Arthroscopic Treatment of Resistant Cases of Patellofemoral Pain by Circumpatellar Denervation
Estimated Study Start Date : October 1, 2018
Estimated Primary Completion Date : October 1, 2020
Estimated Study Completion Date : March 1, 2021

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Osteoarthritis

Arm Intervention/treatment
Experimental: pre operative group
pre operative group with patellofemoral pain resistant to medical and physiotherapy assessment by pre operative knee score arthroscopic circumpatellar denervation with or without lat. Patellar facetectomy
Procedure: arthroscopic circumpatellar denervation with or without lat. Patellar facetectomy
arthroscopic management of resistant cases anterior knee pain to medical and physiotherapy pre operative group ( by circumpatellar denervation plus or minus lat. facetectomy according to stage of O.A ) and Comparison between pre and post-operative results in pain reduction, improving knee joint by using 2 knee scores




Primary Outcome Measures :
  1. The effect of arthroscopic management of resistant cases of patellofemoral osteoarthritis on pain scale. [ Time Frame: all study 2 years average follow up up to 12 months for all cases ]
    The aim is to evaluate the effectiveness of arthroscopic management of anterior knee osteoarthritis in pain reduction in selected cases on a scale from 0 to 10 (10 is the highest sense of pain) followed by an average follow up to 12 months ( 6th weeks ,3rd month ,6th month , 12th month)


Secondary Outcome Measures :
  1. The effect of arthroscopic management of resistant cases of patellofemoral osteoarthritis in improving Anterior Knee Pain Scale (AKPS) / (Kujala Scale) [ Time Frame: We will compare the score before and after the surgery and check if it is statically significant.followed by an average follow up to 12 months ( 6th weeks ,3rd month ,6th month , 12th month) ]
    this score (Kujala et al1993) is measuring 13 items related to knee pain,knee joint function and quality of life.the items include (Limp, Support, Walking, Stairs climbing, Squatting, Running, Jumping, Prolonged sitting with the knees flexed, Pain, Swelling, Abnormal painful kneecap (patellar) movements (subluxations), Atrophy of thigh and Flexion deficiency. Maximum score of the questionnaire is 100 (the higher the better).We will compare the score before and after the surgery and check if it is statically significant.followed by an average follow up to 12 months ( 6th weeks ,3rd month ,6th month , 12th month)

  2. The effect of arthroscopic management of resistant cases of patellofemoral osteoarthritis in improving Knee Injury and Osteoarthritis Outcome Score(KOOS). [ Time Frame: We will compare the score before and after the surgery and check if it is statically significant.followed by an average follow up to 12 months ( 6th weeks ,3rd month ,6th month , 12th month) ]
    This score measuring 42 items in 5 aspects ( knee-related Quality of Life, Pain, Function in daily living, Sport and Recreation and other Symptoms).the score scales from 0 to 100 (the higher the better).We will compare the score before and after the surgery and check if it is statically significant.followed by an average follow up to 12 months ( 6th weeks ,3rd month ,6th month , 12th month)



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Ages Eligible for Study:   18 Years to 50 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria
  1. Inclusion criteria:

    1. Age between 18 to 50
    2. Ant. Knee pain
    3. Resistant cases to medical and physiotherapy after 6 months.
    4. Intact tibiofemoral joints or early O.A , and intact meniscus, cruciate ligaments, and Collateral ligaments.
  2. Exclusion criteria:

    1. Old Age >50 or < 18
    2. Combined cases with severe tibiofemoral OA (either deformity or malignment).
    3. Combined injury to (collateral ligaments, meniscus, cruciate ligament)
    4. Cases with tibial torsion
    5. Malalignment that necessitate correction.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03615976


Contacts
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Contact: muhammad kamel, MBBCH +201018585095 muhammadkamel14@gmail.com
Contact: Hesham El kady, PROFESSOR +201005211797 hesham.elkadi@med.au.edu.eg

Sponsors and Collaborators
Assiut University
Investigators
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Study Director: Hatem Galal Zaki, PROFESSOR ASSIUT HOSPITAL UNIVERSITY

Publications:
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Responsible Party: muhammad kamel muhammad sayed, dr: muhammad kamel muhammad sayed, Assiut University
ClinicalTrials.gov Identifier: NCT03615976     History of Changes
Other Study ID Numbers: arthroscopy in P.F.O.A
First Posted: August 6, 2018    Key Record Dates
Last Update Posted: August 6, 2018
Last Verified: August 2018

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No

Keywords provided by muhammad kamel muhammad sayed, Assiut University:
arthroscopy
Patellofemoral Osteoarthritis

Additional relevant MeSH terms:
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Patellofemoral Pain Syndrome
Joint Diseases
Musculoskeletal Diseases