Comparison of Cervical Ultrasound and Echoscintigraphy for Preoperative Localization Diagnosis in Primary Hyperparathyroidism (ECHOPARAT)
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|ClinicalTrials.gov Identifier: NCT03605472|
Recruitment Status : Recruiting
First Posted : July 30, 2018
Last Update Posted : July 30, 2018
The biological diagnosis of the primary hyperparathyroidism is now facilitated by the reliability of the balance of phosphate and calcium and the dosage of parathyroid hormone (PTH).
This diagnosis of preoperative localization is important as surgery are now targeted to the responsible lesion.
The "gold standard" for this localization is the cervical ultrasound exploring the usual sites of adenomas and a MIBI scintigraphy (the parathyroid adenoma significantly concentrating this cell marker).
However, the diagnosis of preoperative localization remains a subject of discussion as to the most appropriate tests. Indeed, the morphological diagnosis is performed at the ultrasound stage in more than half the cases. It is the new performance of this morphological examination that makes it possible to obtain these results.
|Condition or disease||Intervention/treatment||Phase|
|Primary Hyperparathyroidism||Other: cervical ultrasound||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||100 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Comparison of Cervical Ultrasound and Echoscintigraphy for Preoperative Localization Diagnosis in Primary Hyperparathyroidism|
|Actual Study Start Date :||October 5, 2017|
|Estimated Primary Completion Date :||October 5, 2019|
|Estimated Study Completion Date :||March 5, 2020|
Other: cervical ultrasound
cervical ultrasound will be realized by a endocinologist trained in the cervical ultrasound
- Adenoma parathyroid diagnosed using cervical ultrasound [ Time Frame: Day 0 ]Adenoma parathyroid diagnosed using cervical ultrasound. Cervical ultrasound will be realized by a endocrinologist trained in the cervical ultrasound and not informed of the results of the echoscintigraphy
- Adenoma parathyroid diagnosed using echoscintigraphy [ Time Frame: Day 0 ]Adenoma parathyroid diagnosed using echoscintigraphy. Echoscintigraphy will be realized by a nuclear physician not informed of the results of the cervical ultrasound
- Adenoma parathyroid diagnosed using anatomopathology [ Time Frame: Day 0 ]Adenoma parathyroid diagnosed by anatomopathologist, after surgery.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03605472
|Contact: Brigitte DELEMERfirstname.lastname@example.org|
|Contact: Brigitte DELEMER 0326788101 ext 0033 email@example.com|