Yield of Colonoscopy in Children With Rectal Bleeding
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| ClinicalTrials.gov Identifier: NCT03596320 |
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Recruitment Status :
Not yet recruiting
First Posted : July 23, 2018
Last Update Posted : July 23, 2018
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| Condition or disease | Intervention/treatment |
|---|---|
| Colonic Diseases | Procedure: colonoscopy |
Rectal bleeding is a source of anxiety for both children and parents and is frequently encountered clinical complaint in routine practice in pediatric patient . Lower gastrointestinal bleeding means bleeding from sites distal to the ligament of treitz and presents as rectal bleeding while passage of bright red blood from the rectum is called hematochezia.
The etiology of rectal bleeding is different in children than in adult according to age group which enables physicians to make appropriate differential diagnosis. There are several etiologies for rectal bleeding in pediatric practice ranging from mild condition requiring little or no treatment to severe and life-threating ones requiring immediate intervention. The etiologies include anal fissure, food allergy, infectious enterocolitis, Meckel'sdiverticulum, intussusceptions, volvulus, lymphonodular hyperplasia, inflammatory bowel disease, angiodysplasia, hemorrhoids, and hemolytic -uremic syndrome. Common causes of bleeding per rectum in children vary between studies . Once the bleeding is suspected to be coming from lower gastrointestinal tract it warrant an evaluation in all cases by proctosigmoidoscopy followed by colonoscopy .
Colonoscopy is the examination of choice for diagnosis and management of bleeding per rectum in children . The benefits of colonoscopy include identification of the site of bleeding regardless of the rate or presence of bleeding through visualization the entire length of the colon often include the distal ileum by possibility of endoscpic intervention and biopsy taking to make and confirm the diagnosis and follow up evaluation, so gastrointestinal endoscopy with biopsy is an essential tool for diagnosis of crohns disease and ulcerative colitis in children, as well as therapeutical intervention of colonoscopy by hemostasis, removing polyps, dilating stricture or decompressing the obstructed bowel .
Colonoscopy is considered a safe and low risk procedure. Complications of colonoscopy are rare and usually minor, as adverse effects of sedative medicine as (nausea,vomiting or allergies) can ocurr.
Bleeding after colonoscopy is usually minimal but may follow mucous biopsy or polypectomy, Perforation is very rare but it is the most serious complication of colonoscopy in children, it is usually related to polypectomy and can be successfully managed with surgical intervention. In case of infection in which cause the child will be given antibiotics.
| Study Type : | Observational |
| Estimated Enrollment : | 100 participants |
| Observational Model: | Other |
| Time Perspective: | Cross-Sectional |
| Official Title: | Yield of Colonoscopy in Children With Bleeding Per Rectum Attending Gastrointestinal Endoscopic Unit In Assuit University Children Hospital |
| Estimated Study Start Date : | July 20, 2018 |
| Estimated Primary Completion Date : | May 30, 2019 |
| Estimated Study Completion Date : | July 30, 2019 |
- Procedure: colonoscopy
description of the results of colonoscopy im managment of children with rectal bleeding
- Number of participants free and recurrance of colonic disease after colonoscopy procedure [ Time Frame: 2 year ]Number of participants were monitored with recurrance of rectal bleeding and underwent colonoscopy up to 2 years
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| Ages Eligible for Study: | 1 Month to 18 Years (Child, Adult) |
| Sexes Eligible for Study: | All |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Probability Sample |
Inclusion Criteria:
- all children with rectal bleeding underwent colonoscopy
Exclusion Criteria:
- children underwent colonoscopy rather than rectal bleeding
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03596320
| Contact: Zeinab Mohi eldeen, Professor | +020122397149 | Zeenabmohielden1957@gmail.com | |
| Contact: Nagla Hassan, Professor | +020111187227 | Nhi_af@hotmail.com |
| Egypt | |
| Assiut U | |
| Assiut, Egypt | |
| Contact: Zeinab Mohi eldeen, Professor +0201223971490 Zeenabmohielden1957@gmail.com | |
| Contact: Nagla Hassan +0201111872237 Nhi_af@hotmail.com | |
| Principal Investigator: | Soha Iraqi | Assiut University |
Additional Information:
Tringali A,Balassone V,Angelis P.Complication in pediatric colonoscopy.2015;30(5):825-39.
Publications of Results:
Other Publications:
| Responsible Party: | SHIraqi, principle investigator, Assiut University |
| ClinicalTrials.gov Identifier: | NCT03596320 |
| Other Study ID Numbers: |
crbchildren |
| First Posted: | July 23, 2018 Key Record Dates |
| Last Update Posted: | July 23, 2018 |
| Last Verified: | July 2018 |
| Individual Participant Data (IPD) Sharing Statement: | |
| Plan to Share IPD: | No |
| Studies a U.S. FDA-regulated Drug Product: | No |
| Studies a U.S. FDA-regulated Device Product: | No |
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Colonic Diseases Intestinal Diseases Gastrointestinal Diseases Digestive System Diseases |