Study on the Mechanism of Neurodevelopment Dysplasia of Fetal Brain Caused by ASNS Gene Mutation
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|ClinicalTrials.gov Identifier: NCT03587155|
Recruitment Status : Unknown
Verified July 2018 by Bo Chen, The First Hospital of Jilin University.
Recruitment status was: Recruiting
First Posted : July 16, 2018
Last Update Posted : July 16, 2018
|Condition or disease|
|Asparagine Synthetase Deficiency Genetic Diseases, Inborn|
|Study Type :||Observational|
|Estimated Enrollment :||10 participants|
|Official Title:||Study on the Mechanism of Neurodevelopment Dysplasia of Fetal Brain Caused by ASNS Gene Mutation|
|Actual Study Start Date :||October 28, 2017|
|Estimated Primary Completion Date :||December 2018|
|Estimated Study Completion Date :||December 2020|
Embryo or infant with ASNS mutation.
Embryo or infant without ASNS mutation.
- Effect of ASNS gene mutation on RNA expression in prefrontal cortex cells of brain tissue [ Time Frame: 2018.06-2020.12 ]Detect RNA expression in prefrontal cortex cells by single cell RNA sequencing.
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03587155
|Contact: Bo Chen, M.D., Ph.D.||+86 firstname.lastname@example.org|
|Contact: Xinyu Hong, M.D., Ph.D.||email@example.com|
|Principal Investigator:||Bo Chen, M.D., Ph.D.||The First Hospital of Jilin University|