Investigation of the Changes of Brain Structure and Function in Premature Ejaculation Patients and the Effects of Dapoxetine on Central Neural Activity in Premature Ejaculation Patients
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|ClinicalTrials.gov Identifier: NCT03583112|
Recruitment Status : Recruiting
First Posted : July 11, 2018
Last Update Posted : August 24, 2018
|Condition or disease||Intervention/treatment||Phase|
|Premature Ejaculation||Drug: Dapoxetine Hydrochloride Tablet Drug: Placebo Tablet||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||100 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)|
|Primary Purpose:||Basic Science|
|Official Title:||Investigation of the Changes of Brain Structure and Function in Premature Ejaculation Patients and the Effects of Dapoxetine on Central Neural Activity in Premature Ejaculation Patients|
|Actual Study Start Date :||July 10, 2018|
|Estimated Primary Completion Date :||December 2018|
|Estimated Study Completion Date :||December 2018|
Active Comparator: Dapoxetine
In this group, patients received one dapoxetine hydrochloride tablet before MRI scan.
Drug: Dapoxetine Hydrochloride Tablet
oral one dapoxetine hydrochloride tablet before MRI scan
Placebo Comparator: Placebo
In this group, patients received placebo tablet before MRI scan.
Drug: Placebo Tablet
oral one placebo tablet before MRI scan.
- Resting-state brain function measured by Functional magnetic resonance imaging [ Time Frame: One day ]We will use several indicators to assess the resting-state brain function based on fMRI analysis, including regional homogeneity,Amplitude of Low Frequency Fluctuations, and functional connectivity.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03583112
|Contact: xuejuan Yangemail@example.com|
|The ART Center, The Northwest Women's and Children's Hospital,||Recruiting|
|Xi'an, Shaanxi, China, 710003|
|Contact: Xuejuan Yang|
|Principal Investigator:||Gao||The ART Center, The Northwest Women's and Children's Hospital|