Prospective Memory Training in Parkinson Disease
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|ClinicalTrials.gov Identifier: NCT03582670|
Recruitment Status : Recruiting
First Posted : July 11, 2018
Last Update Posted : July 12, 2018
|Condition or disease||Intervention/treatment||Phase|
|Parkinson Disease||Behavioral: Strategy Training Behavioral: Process Training Behavioral: Control Group||Not Applicable|
Show Detailed Description
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||90 participants|
|Intervention Model:||Factorial Assignment|
|Primary Purpose:||Supportive Care|
|Official Title:||Prospective Memory Training in Parkinson Disease|
|Actual Study Start Date :||October 1, 2017|
|Estimated Primary Completion Date :||December 1, 2021|
|Estimated Study Completion Date :||June 1, 2022|
Experimental: Strategy Training Intervention
Study participants receive specific memory strategy training with training games, as well as feedback on accuracy and performance.
Behavioral: Strategy Training
Participants will attend four strategy training sessions total. In sessions 1 and 2, in addition to teaching about event- and time-based tasks, the trainer teaches the participant specific strategies for each type of task (implementation intentions for event-based and strategic clock-checking for time-based). In sessions 3 and 4, the trainer tells the participant s/he will be practicing both types of tasks in the training games and can support the participant's strategy use if needed. Feedback on accuracy and strategy use are provided after each training game. At the end of each session after completing the training games, the trainer and participant discuss how the strategies can be applied to the participant's real-life prospective memory goals, and the trainer helps the participant develop written action plans to do so. Plans are reviewed (and modified if necessary) at each session.
Active Comparator: Process Training
Study participants attend training sessions and complete training games, but receive no specific strategy training
Behavioral: Process Training
Participants will attend four process training sessions in this group. In sessions 1 and 2, the trainer teaches the participant about event- and time-based prospective memory tasks, respectively. In sessions 3 and 4, the trainer simply tells the participant that s/he will be practicing both types of tasks in the training games. In all sessions, the participant completes the training games with no strategy instruction from the trainer. Feedback on accuracy is provided after each training game. At the end of each session after completing both training games, the trainer reminds the participant of his/her real-life prospective memory goals, provides a handout that lists the goals, and instructs the participant to try to complete them as intended. Of note, even this minimal level of discussion of real-life cognitive tasks is not typical of process training interventions, but we include it to control for that which is occurring in the strategy training group.
Study participants do not attend any strategy training sessions.
Behavioral: Control Group
Participants in this group do not attend any sessions during the time the other groups are participating in the Strategy or Process Training
- Virtual Week [ Time Frame: 4 to 6 weeks ]A computerized board game that simulates daily life and real-world prospective memory challenges. Each circuit represents one day in which the participant completes time-appropriate activities and makes choices about them (i.e. the ongoing activity). Each day has 8 prospective memory tasks (4 event based, 4 time based). Participants complete a practice day and then three test days, with equivalent versions counterbalanced across Pre and Post testing. The main outcome variable is the proportion of correct prospective memory responses for each task type (12 event based, 12 time based). Change of performance on the Virtual Week from the Pre- and Post-session will be measured.
- Prospective and Retrospective Memory Questionnaire [ Time Frame: Through completion of the study, up to 16 weeks. ]Used to rate the participant's everyday retrospective and prospective memory. Change in scores on this questionnaire will be measured.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03582670
|Contact: Erin Foster, PhD, OTDfirstname.lastname@example.org|
|Contact: Tasha Doty, MAemail@example.com|
|United States, Missouri|
|Washington University School of Medicine||Recruiting|
|Saint Louis, Missouri, United States, 63110|
|Contact: Erin Foster 314-286-1638 firstname.lastname@example.org|