Energy Metabolism for the Patients With Pulmonary Mycobacterium Avium Complex
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|ClinicalTrials.gov Identifier: NCT03550820|
Recruitment Status : Active, not recruiting
First Posted : June 8, 2018
Last Update Posted : October 29, 2019
|Condition or disease|
|Pulmonary MAC Energy Metabolism Emaciation|
Patients with pulmonary MAC with a lower BMI than healthy individuals also have a significantly poorer prognosis than those of normal weight. Emaciation in such patients is thought to be caused by destruction of lung structure from disease progression and an increased resting metabolic rate caused by the increased load from breathing; however, causes of emaciation and details of energy metabolism in these patients have not been studied.
Elucidating details of energy metabolism and causes of emaciation in patients with pulmonary MAC could provide the basis for improvement in nutritional status and activities of daily living through early nutrition therapy and rehabilitation. We propose to clarify the following:
Energy metabolism in patients with pulmonary MAC, including resting metabolic rate, calorie intake and consumption, and hormonal secretions.
Relation between energy metabolism and degree of pulmonary MAC progression.
|Study Type :||Observational|
|Estimated Enrollment :||105 participants|
|Official Title:||Energy Metabolism for the Patients With Pulmonary Mycobacterium Avium Complex|
|Actual Study Start Date :||May 1, 2018|
|Estimated Primary Completion Date :||May 2021|
|Estimated Study Completion Date :||May 2021|
- Relation between energy balance and pulmonary MAC severity [ Time Frame: Three years ]
- Relation between inflammation (CRP et.) and pulmonary MAC severity [ Time Frame: Three years ]
- Relation between bone mineral density and pulmonary MAC severity [ Time Frame: Three years ]
- Relation between hormone secretion and pulmonary MAC severity [ Time Frame: Three years ]
- Relation between pulmonary function and pulmonary MAC severity [ Time Frame: Three years ]
Biospecimen Retention: Samples Without DNA
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Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03550820
|National Hospital Organization Minami Kyoto Hospital|
|Joyo, Kyoto, Japan, 610-0113|