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Right Ventricular Function Change After PCI to Right Coronary Artery

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT03543345
Recruitment Status : Unknown
Verified June 2018 by Hazim Alaa, Assiut University.
Recruitment status was:  Recruiting
First Posted : June 1, 2018
Last Update Posted : June 19, 2018
Sponsor:
Information provided by (Responsible Party):
Hazim Alaa, Assiut University

Brief Summary:
Proximal RCA occlusions were very often found among men with fatal pre-hospital MI; whereas left-sided coronary occlusions were significantly more frequent in hospital-admitted survivors of MI. Left-sided coronary occlusions may be associated with a more favorable pre-hospital phase of acute MI compared to proximal RCA occlusions. Proximal RCA occlusion increases the risk of arrhythmia and shock leading to increase the mortality. Sinus bradycardia and cardiogenic shock accounts for the majorities of the mortalities of RCA occlusion

Condition or disease Intervention/treatment
Right Coronary Artery Occlusion Diagnostic Test: echocardiography study

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Study Type : Observational
Estimated Enrollment : 50 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: The Changes in The Right Ventricular Function After Elective Percutaneous Coronary Intervention in Patients With Right Coronary Artery Occlusion
Actual Study Start Date : June 1, 2018
Estimated Primary Completion Date : August 15, 2018
Estimated Study Completion Date : August 28, 2018

Intervention Details:
  • Diagnostic Test: echocardiography study

    Patients with right coronary artery occlusion lesion will be subjected to:

    • Written consent.
    • Complete history.
    • Complete physical examination.
    • Trans-thoracic echocardiography assessment of the right ventricular function before PCI to the RCA
    • Follow up Trans-thoracic echocardiography assessment of the right ventricular function four weeks after the PCI.


Primary Outcome Measures :
  1. Change in RV function PCI to RCA [ Time Frame: 3 months ]
    The aim of the study is to determine the impact of elective PCI of RCA on RV systolic and diastolic functions.



Information from the National Library of Medicine

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Ages Eligible for Study:   40 Years to 75 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients subjected to elective PCI due to right coronary artery occlusion. Patients between 40 and 75 years old from the both genders
Criteria

Inclusion Criteria:

  • Patients subjected to elective PCI due to right coronary artery occlusion. Patients between 40 and 75 years old from the both genders

Exclusion Criteria:

  1. History of chronic respiratory condition and PHTN
  2. Patients with previous percutaneous coronary intervention (PCI) or coronary artery bypass graft surgery (CABG).
  3. History of valvular surgery.
  4. Patients with significant rheumatic vavular heart disease.
  5. Presence of persistant arrythemia
  6. Patients with End stage renal disease.
  7. Patients with End stage liver disease.
  8. Haemodynamically unstable patients.
  9. Patients with previous Myocardial infarction.
  10. Patients with Ischemic Dilated Cardiomyopathy.
  11. Patients with pericardial disease.
  12. Patients with congenital intra-cardiac shunt.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03543345


Contacts
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Contact: Hazim A. Kaml, MBcCH +201118186565 ihazim1990@gmail.com
Contact: Mahmoud A. Abd Elbaset, MD +201112786731

Locations
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Egypt
Al Azhar university Recruiting
Assiut, Egypt
Contact: Hazim alaa    +201118186565    ihazim1990@gmail.com   
Sponsors and Collaborators
Assiut University
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Responsible Party: Hazim Alaa, Principal investigator, Assiut University
ClinicalTrials.gov Identifier: NCT03543345    
Other Study ID Numbers: HAZ190
First Posted: June 1, 2018    Key Record Dates
Last Update Posted: June 19, 2018
Last Verified: June 2018

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Keywords provided by Hazim Alaa, Assiut University:
RCA
PCI
right ventricular function
Additional relevant MeSH terms:
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Coronary Occlusion
Vascular Diseases
Cardiovascular Diseases
Coronary Disease
Myocardial Ischemia
Heart Diseases