The Effects of a Jump Rope Exercise Program on Vascular Health, Inflammatory Markers in Prehypertensive Adolescent Girls
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|ClinicalTrials.gov Identifier: NCT03534427|
Recruitment Status : Completed
First Posted : May 23, 2018
Results First Posted : August 14, 2019
Last Update Posted : August 14, 2019
Pusan National University
Information provided by (Responsible Party):
Songyoung Park, Pusan National University
The purpose of this study was to examine the impact of a 12-week jump rope exercise program on blood pressure, arterial stiffness, vasodilating and vasoconstricting factors, inflammatory markers, and body composition in prehypertensive adolescent girls. Forty prehypertensive adolescent girls participated in this study. The girls were randomly divided into the jump rope exercise intervention group (EX, n=20) and control group (CON, n=20). The EX group performed a jump rope training program at 40-70% of their heart rate reserve (HRR) 5 days/week for 12 weeks (sessions 50 minutes in duration). The CON group did not participate in any structured or unstructured exercise protocol. Blood pressure, arterial stiffness, plasma nitrate/nitrite levels, endothelin-1, C-reactive protein, and body composition were measured before and after the 12-weeks study.
|Condition or disease||Intervention/treatment||Phase|
|Prehypertension Blood Pressure Abdominal Obesity Adiposity||Other: Jump rope exercise intervention||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||40 participants|
|Intervention Model:||Parallel Assignment|
|Intervention Model Description:||exercise intervention group, control group|
|Masking:||None (Open Label)|
|Primary Purpose:||Health Services Research|
|Official Title:||The Effects of a 12-Week Jump Rope Exercise Training Program on Arterial Stiffness, Vasodilating and Vasoconstricting Factors, Inflammatory Markers, and Body Composition in Prehypertensive Adolescent Girls|
|Actual Study Start Date :||June 5, 2016|
|Actual Primary Completion Date :||February 10, 2018|
|Actual Study Completion Date :||March 21, 2018|
No Intervention: Control group
No exercise intervention
Experimental: Jump rope exercise intervention
The jump rope exercise program was performed for 50 minutes with 5 minutes of warm-up and cool-down per day, 5 times a week for 12 weeks. The program consisted of various main jump rope exercises (1 line 2 jump, jumping feet together, running jumping, open side jump, open back and forth jump, rock paper scissor jump). The warm-up and cool down consisted of static stretching, walking, and jogging. Intensity of exercise was gradually increased from 40-50% heart rate reserve (HRR) in weeks 1-4 and to 60-70% HRR in weeks 9-12. Each training session was supervised by the researchers. Every subject wore a heart rate monitor during the whole training session in order to maintain the designated training intensity.
Other: Jump rope exercise intervention
12-week jump rope exercise program
Primary Outcome Measures :
- Arterial Stiffness [ Time Frame: 12 weeks ]Arterial stiffness was measured as measurement of brachial to ankle pulse-wave velocity. This indicates peripheral arterial stiffness, as it measures how quickly a pulse wave propagates from one point to another.
- Endothelin-1 [ Time Frame: 12 weeks ]Levels of Endothelin-1 in blood were measured by Endothelin-1 enzyme immunoassay kit.
- Body Mass [ Time Frame: 12 weeks ]Body mass was measured to nearest 0.1 kg.
- Height [ Time Frame: 12 weeks ]Height was measured to nearest 1 cm.
- Waist Circumference [ Time Frame: 12 weeks ]Waist circumference was measured at midpoint between the lower rib and the iliac crest at the end of a normal expiration using a tape measure.
- Body Fat [ Time Frame: 12 weeks ]Percent body fat (%) was determined using a bioelectrical impedance-meter.
- Lean Body Mass [ Time Frame: 12 weeks ]Lean body mass (kg) was determined using a bioelectrical impedance-meter.
- Nitrate/Nitrite Levels [ Time Frame: 12 weeks ]Nitrate and nitrite levels were assayed using a Griess assay kit.
- C-reactive Protein [ Time Frame: 12 weeks ]C-reactive protein was assessed using an enzyme immunoassay assay kit
- Systolic Blood Pressure [ Time Frame: 12 weeks ]Blood pressure was measured in duplicate using an automated sphygmomanometer. The average of the two was recorded as the resting blood pressure.
- Diastolic Blood Pressure [ Time Frame: 12 weeks ]
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