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Trial record 12 of 57 for:    Recruiting, Not yet recruiting, Available Studies | Arthroscopy

Effect of Pregabalin on Postoperative Analgesia

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ClinicalTrials.gov Identifier: NCT03530280
Recruitment Status : Not yet recruiting
First Posted : May 21, 2018
Last Update Posted : May 21, 2018
Sponsor:
Information provided by (Responsible Party):
Fatma Kavak Akelma, Ankara Diskapi Training and Research Hospital

Brief Summary:
knee arthroscopy under spinal anesthesia were included in this study.

Condition or disease Intervention/treatment Phase
Postoperative Pain After Knee Arthroscopy Drug: pregabalin (lyrica) Drug: PLacebo Drug: adductor channel block including bupivacaine Not Applicable

Detailed Description:
Anesthesiologists I or II scheduled to undergo knee arthroscopy under spinal anesthesia are included in this study. The first group is administered 300 mg oral pregabalin 1 hour before surgery. The second group is the control group; patients in this group are administered a placebo capsule 1 hour before surgery.The third group is administered a placebo capsule 1 hour before surgery and postoperative adductor canal block is performed. All patients will be received postoperative a tramadol i.v. patient control analgesia device. At the end of 24 hours, the total amount of tramadol consumed by the patient will be recorded from the patient control analgesia. NRS score, white fast track will be questioned.

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Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 48 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Participant)
Primary Purpose: Other
Official Title: Effect of Pregabalin on Postoperative Analgesia After Arthroscopic Knee Surgery
Estimated Study Start Date : June 1, 2018
Estimated Primary Completion Date : October 1, 2018
Estimated Study Completion Date : December 1, 2018

Resource links provided by the National Library of Medicine

Drug Information available for: Pregabalin

Arm Intervention/treatment
Active Comparator: pregabalin (lyrica)
pregabalin (lyrica) 300 mg preoperative 1 hour before
Drug: pregabalin (lyrica)
preoperative pregabalin or postoperative adductor block will perform.
Other Name: adductor canal block

Placebo Comparator: placebo group
a placebo capsule 1 hour before surgery
Drug: PLacebo
Placebo

Active Comparator: adductor channel block group
This group will receive adductor channel block including 20 ml of 0.25% bupivacaine
Drug: adductor channel block including bupivacaine
adductor channel block including 20 ml of 0.25% bupivacaine




Primary Outcome Measures :
  1. 11-point numerical rating scale (NRS) [ Time Frame: 24 hours ]
    11-point numerical rating scale for pain (0='no pain' and 10='worst pain possible pain') were explained.

  2. tramadol consumption [ Time Frame: 24 hours ]
    24 hours tramadol consumption will be recorded as milligrams



Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 70 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Patients between the ages of 18 and 70 years
  • American Society of Anesthesiologists I or II
  • Scheduled to undergo knee arthroscopy

Exclusion Criteria:

  • allergic to any medicines
  • History of drug or alcohol abuse,
  • Opioids or sedative medications
  • History of psychiatric conditions
  • Pregnant or lactating women

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03530280


Contacts
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Contact: fatma kavak akelma 905327079113 fatmakavak@yahoo.com

Sponsors and Collaborators
Ankara Diskapi Training and Research Hospital

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Responsible Party: Fatma Kavak Akelma, specialist doctor, Ankara Diskapi Training and Research Hospital
ClinicalTrials.gov Identifier: NCT03530280     History of Changes
Other Study ID Numbers: pregabalin
First Posted: May 21, 2018    Key Record Dates
Last Update Posted: May 21, 2018
Last Verified: May 2018
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No

Keywords provided by Fatma Kavak Akelma, Ankara Diskapi Training and Research Hospital:
pregabalin
adductor canal block
postoperative pain

Additional relevant MeSH terms:
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Pain, Postoperative
Postoperative Complications
Pathologic Processes
Pain
Neurologic Manifestations
Signs and Symptoms
Bupivacaine
Pregabalin
Anesthetics, Local
Anesthetics
Central Nervous System Depressants
Physiological Effects of Drugs
Sensory System Agents
Peripheral Nervous System Agents
Analgesics
Anticonvulsants
Calcium Channel Blockers
Membrane Transport Modulators
Molecular Mechanisms of Pharmacological Action
Calcium-Regulating Hormones and Agents
Anti-Anxiety Agents
Tranquilizing Agents
Psychotropic Drugs