Establishing the Diagnosis Standard and Analysis the Risk Factors of POI in Chinese Women
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The study aims to establishing the diagnosis standard of POI and analyzing the risk factors in Chinese women.
Condition or disease
Primary Ovarian Insufficiency
Premature ovarian insufficiency (POI) is a clinical syndrome defined by loss of ovarian activity before the age of 40 years. The POI guideline development group of ESHRE recommends the following diagnostic criteria: oligo/amenorrhea for at least 4 months and an elevated follicle stimulating hormone (FSH) level ＞25 mIU/mL on two occasion ＞4 weeks apart. But there still no diagnosis standard of POI in Chinese.The study aims to establishing the diagnosis standard of POI and analyzing the risk factors in Chinese women.
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Ages Eligible for Study:
12 Years to 39 Years (Child, Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Female under the condition of diminished ovarian reserve were enrolled in the study. The condition of diminished ovarian reserve may be the early stage of premature ovarian insufficiency.
The length of menstrual cycle longer than 35 days or shorter than/amenorrhea
Serum FSH levels ≥10mIU/ml/ serum AMH levels ≤1.0pg/ml/ AFC ≤7, on at least two occasion ＞4 weeks apart