Mucociliary Clearance, Airway Inflammation and Nasal Symptoms in Urban Motorcycle-drivers
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|ClinicalTrials.gov Identifier: NCT03510585|
Recruitment Status : Completed
First Posted : April 27, 2018
Last Update Posted : April 27, 2018
|Condition or disease||Intervention/treatment||Phase|
|Attitude to Health||Other: saline and sniffing Other: sniffing||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||24 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Triple (Participant, Investigator, Outcomes Assessor)|
|Official Title:||Mucociliary Clearance, Airway Inflammation and Nasal Symptoms in Urban Motorcycle-drivers|
|Study Start Date :||July 2012|
|Actual Primary Completion Date :||August 2012|
|Actual Study Completion Date :||August 2012|
Experimental: saline and sniffing
This RRC is the combination of positioning (laying down), sniffing (only one side), throat vibration and saline instillation. And then the other side.
Other: saline and sniffing
This technique is a combination of positioning (laying down), saline instilation (5 ml in each side), sniffing (the side that received saline instilation) and throat vibration. Then the other side.
Placebo Comparator: sniffing
Pacient will be in a lay down condition and will perform sniffing with throat vibration several times each side (but with no saline instillation)
This technique is a combination of positioning (laying down), sniffing (the side that received saline instilation) and throat vibration. Then the other side.
- Nasal mucociliary clearance [ Time Frame: 15 days ]Saccharine transit time test.
- Mucus physical properties [ Time Frame: 15 days ]Contact angle
- Upper airway symptoms [ Time Frame: 15 days ]Sinonasal Outcome Questionnaire -20
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03510585
|Universidade Federal de Minas Gerais|
|Belo Horizonte, Minas Gerais, Brazil|
|Faculdade de Medicina da Universidade de São Paulo|
|Sao Paulo, Brazil, 1246-903|
|Study Director:||Paulo HN Saldiva, PhD||University of Sao Paulo|