ClinicalTrials.gov
ClinicalTrials.gov Menu
Trial record 4 of 24 for:    Recruiting, Not yet recruiting, Available Studies | "Lewy Body Disease"

Patients With Alzheimer's Disease or Related Youth Disease (PARMAAJJ)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT03508024
Recruitment Status : Recruiting
First Posted : April 25, 2018
Last Update Posted : April 25, 2018
Sponsor:
Information provided by (Responsible Party):
University Hospital, Lille

Brief Summary:
This study aims to determine factors related to diagnosis delay for patients with young onset dementia (first symptoms before 60 years old) who live in North of France.

Condition or disease
Alzheimer Disease, Early Onset Lewy Body Disease Frontotemporal Lobar Degeneration

Study Type : Observational
Estimated Enrollment : 220 participants
Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Patients With Alzheimer's Disease or Related Youth Disease
Actual Study Start Date : January 5, 2018
Estimated Primary Completion Date : January 2019
Estimated Study Completion Date : January 2019





Primary Outcome Measures :
  1. the delay between the diagnosis and the first symptomsIdentification of factors related with diagnosis delay [ Time Frame: 10 years ]
    To determine the factors associated with diagnostic delay in young patients (early symptoms before age 60) with Alzheimer's disease or related degenerative disease (Fronto-temporal Lobar Degeneration , Lewy Body Dementia )


Secondary Outcome Measures :
  1. Comparison of patient profiles followed at the CMRR-CNR-MAJ Lille and those who are not. [ Time Frame: 10 years ]
    The different profiles are defined according to composite measures of socio-demographic type

  2. Comparison of patients characteristics followed at the CMRR-CNR-MAJ Lille and those who are not.Impact of the diagnosis on YOD [ Time Frame: 10 years ]
    The different characteristics are defined according to composite measures of socio-demographic type

  3. the percentage of patients who have had a lack of information about the disease and possible aids [ Time Frame: 10 years ]
    Identification of medico-social issues taht have been encountered by YOD patients during the care

  4. the percentage of refusal or delay of treatment of certain medico-social aids by the competent authorities [ Time Frame: 10 years ]
    Identification of medico-social issues taht have been encountered by YOD patients during the care



Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Patients with a diagnosis of Alzheimer disease, Lewy Bodies Dementia or FrontoTemporal Lobar Degeneration and their caregivers
Criteria

Inclusion Criteria:

As part of this study, patients will be considered:

  • Residing in the departments of Nord (59) and Pas-de-Calais (62),
  • whose diagnosis of Alzheimer's disease or related illness (DLFT, DCL) was made and announced,
  • Whose diagnosis of illness was made after 2007
  • whose first symptoms appeared before the age of 60 Patients included in the COMAJ cohort and those who completed the Pathways medical and social booklet will have to meet these criteria to be selected for this study.

As part of the survey, caregivers of patients meeting the above criteria and the following two will be recruited:

  • Having consulted or being followed by liberal neurologists or in hospital memory consultations (excluding CMRR-CNR-MAJ Lille) of the departments of Nord and Pas-de-Calais,
  • Not monitored at the CMRR-CNR-MAJ Lille (ad hoc notice possible). The caregiver is defined as a family member or friend who helps regularly by doing the necessary tasks so that the sick person can keep as much autonomy as possible.

Exclusion Criteria:

  • aged under 18
  • no social coverage
  • refusal to sign informed consent form

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03508024


Contacts
Contact: Florence Pasquier, MD, PhD 320445785 ext +33 florence.pasquier@chru-lille.fr

Locations
France
Hôpital Roger Salengro, CHRU Recruiting
Lille, France
Principal Investigator: Florence Pasquier, MD, PhD         
Sponsors and Collaborators
University Hospital, Lille
Investigators
Principal Investigator: Florence Pasquier, MD, PhD University Hospital, Lille

Responsible Party: University Hospital, Lille
ClinicalTrials.gov Identifier: NCT03508024     History of Changes
Other Study ID Numbers: NI_2016_39
2017-A00486-47 ( Other Identifier: ID-RCB number, ANSM )
First Posted: April 25, 2018    Key Record Dates
Last Update Posted: April 25, 2018
Last Verified: April 2018

Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No

Additional relevant MeSH terms:
Lewy Body Disease
Alzheimer Disease
Frontotemporal Lobar Degeneration
Dementia
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Tauopathies
Neurodegenerative Diseases
Neurocognitive Disorders
Mental Disorders
Parkinsonian Disorders
Basal Ganglia Diseases
Movement Disorders
TDP-43 Proteinopathies
Proteostasis Deficiencies
Metabolic Diseases