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Nanofat Grafting for Treatment of Androgenetic Alopecia

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ClinicalTrials.gov Identifier: NCT03506503
Recruitment Status : Not yet recruiting
First Posted : April 24, 2018
Last Update Posted : May 18, 2018
Sponsor:
Information provided by (Responsible Party):
Hongwei Liu, Jinan University Guangzhou

Brief Summary:
Nowadays, multiple treatment modalities have been applied clinically to treat androgenic alopecia, such as Follicular unit transplantation(FUT), finasteride, platelet-rich plasma injection(PRP), etc. In this clinical trial, the investigators aim to analyze the effect of nanofat grafting on treating androgenic alopecia in male.

Condition or disease Intervention/treatment Phase
Androgenic Alopecia Procedure: Nanofat grafting Not Applicable

Detailed Description:

The investigators will treat the hair loss area of a patient by processed nanofat grafting. The participants were asked to come back 1、3、6、9、12 months after treatment for further follow-up.

Before and after the treatment, the hair and follicular will be assessed subjectively by satisfaction assessment, dermatoscope.


Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 10 participants
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Nanofat Grafting for Treatment of Androgenetic Alopecia
Estimated Study Start Date : June 1, 2018
Estimated Primary Completion Date : June 1, 2020
Estimated Study Completion Date : June 1, 2020

Resource links provided by the National Library of Medicine


Arm Intervention/treatment
Experimental: processed Nanofat grafting
processed autologous Nanofat will be injected into the area of the scalp with androgenic alopecia.
Procedure: Nanofat grafting
hair loss area will be treated by processed autologous Nanofat grafting




Primary Outcome Measures :
  1. Dermatoscope [ Time Frame: Baseline and at1,3,6,9,12 months after the treatment ]
    the density of hair follicle and diameter of hair will be analized by dermatoscope before and after the treatment of Nanofat grafting.


Other Outcome Measures:
  1. Satisfaction assessments [ Time Frame: 1,3,6,12 months after treatment ]
    the satisfaction will be assessed after the treatment



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Ages Eligible for Study:   18 Years to 50 Years   (Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Male patients with androgenic alopecia aging from 18 to 50.
  • No scars and wounds on the alopecia area.
  • No skin disease or serious cardiovascular disease.
  • Preoperative examinations remain healthy.

Exclusion Criteria:

  • Serious chronic heart, liver, kidney, blood system disease
  • Allergic diseases, skin inflammation or wounds
  • Alopecia but not androgenic alopecia
  • Acute or chronic infection
  • Take anticoagulant drugs
  • Active vitiligo, psoriasis, systemic lupus erythematosus

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03506503


Contacts
Contact: hongwei liu 8613318882096 576654450@qq.com

Locations
China, Guangdong
the first affiliated hospital of Jinan University
Guangzhou, Guangdong, China, 510000
Sponsors and Collaborators
Jinan University Guangzhou

Publications:
Responsible Party: Hongwei Liu, professor, Jinan University Guangzhou
ClinicalTrials.gov Identifier: NCT03506503     History of Changes
Other Study ID Numbers: 2018
First Posted: April 24, 2018    Key Record Dates
Last Update Posted: May 18, 2018
Last Verified: April 2018
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No

Keywords provided by Hongwei Liu, Jinan University Guangzhou:
nanofat
hair loss
prp

Additional relevant MeSH terms:
Alopecia
Alopecia Areata
Hypotrichosis
Hair Diseases
Skin Diseases
Pathological Conditions, Anatomical