Investigating Epilepsy: Screening and Evaluation
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|ClinicalTrials.gov Identifier: NCT03478852|
Recruitment Status : Recruiting
First Posted : March 27, 2018
Last Update Posted : June 15, 2021
Epilepsy affects about 1 percent of the U.S. population. Most people with epilepsy respond well to medicine, but some do not. Researchers want people who have diagnosed or suspected epilepsy to participate in ongoing studies. They want to learn more about clinical care for epilepsy. They want fellows and residents to learn more about the care of people with epilepsy.
To learn more about seizures and find ways to best treat people with drug-resistant epilepsy.
Adults and children ages 8 years and older with diagnosed or suspected epilepsy
Participants will be screened with:
Participants will have many visits. They may be admitted to the hospital for several weeks. Their medication might be stopped or changed.
Participants will have many tests:
Blood and urine tests
EEG: Wires attached to the head with paste record brain waves. This may be videotaped.
Thinking and memory tests
MRI: Participants lie on a table that slides in and out of a tube. They perform simple tasks in the tube.
MEG: Participants lie on a table and place their head in a helmet to record brain waves.
PET scan: Participants lie on a table that slides into a machine. A small amount of radioactive dye is injected into their arm with an IV. For the IV, a small tube is inserted into the arm with a needle.
Participants will stay enrolled in this study if they join other epilepsy-related studies. They may be contacted at intervals for follow-up. Their participation will end if they have not been seen clinically for their epilepsy for 3 years.
|Condition or disease|
|Seizures Epilepsy Epilepsy, Temporal Lobe Partial Epilepsy|
|Study Type :||Observational|
|Estimated Enrollment :||500 participants|
|Official Title:||Investigating Epilepsy: Screening and Evaluation|
|Actual Study Start Date :||March 28, 2018|
|Estimated Primary Completion Date :||July 30, 2027|
|Estimated Study Completion Date :||July 30, 2027|
Single arm open enrollment of patients with standard of care treatment and evaluation
- Screening and characterization of patients with drug-resistant epilepsy for epilepsy-related protocols [ Time Frame: Ongoing ]Patients will be screened for eligibility for epilepsy-related research protocols.
- Teaching and training of clinical fellows and residents [ Time Frame: Ongoing ]
- Provision of standard care evaluation and medical management of enrolled patients [ Time Frame: Ongoing ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03478852
|Contact: Aaliyah H Hamidullah-Thiam||(301) firstname.lastname@example.org|
|United States, Maryland|
|National Institutes of Health Clinical Center||Recruiting|
|Bethesda, Maryland, United States, 20892|
|Contact: For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR) 800-411-1222 ext TTY8664111010 email@example.com|
|Principal Investigator:||Sara K Inati, M.D.||National Institute of Neurological Disorders and Stroke (NINDS)|