Study of the Correlation Between Muscle Oxygenation and Motor Function in Children With Neuromuscular Disease. (OXMNM)
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|ClinicalTrials.gov Identifier: NCT03471676|
Recruitment Status : Recruiting
First Posted : March 20, 2018
Last Update Posted : March 20, 2018
Preliminary data underline the fact that muscular deoxygenation during training happens earlier in adult patients suffering from neuromuscular disorders in comparison to controls. Up to date, pediatric data are lacking.
The study aims at demonstrating if a correlation exists between the motor deficiency and the muscular deoxygenation in children suffering from neuromuscular disorders.
|Condition or disease||Intervention/treatment|
|Neuromuscular Diseases in Infants Neuromuscular Diseases in Children||Other: Muscular oximetry|
Preliminary data underline the fact that muscular deoxygenation during training happens earlier in adult patients suffering from neuromuscular disorders in comparison to controls, as it was demonstrated in Becker muscular dystrophy patients and fascioscapulo humeral muscular dystrophy. Moreover, the deoxygenation kinetics was positively correlated to the functional status and the muscular deficiency severity. However, no pediatric study has been conducted on this topic up to date.
The aim of the study is to determine if a correlation exists in children suffering from neuromuscular diseases:
- between muscular oxygenation and the percentage of the 6 minutes walking test performed in the routine medical care
- between muscular oxygenation and the total and D1 motor function measure value
|Study Type :||Observational|
|Estimated Enrollment :||50 participants|
|Official Title:||Study of the Correlation Between Muscle Oxygenation and Motor Function in Children With Neuromuscular Disease.|
|Actual Study Start Date :||February 14, 2018|
|Estimated Primary Completion Date :||February 2019|
|Estimated Study Completion Date :||February 2019|
6 minutes walking test performed in the routine medical care with muscle oximetry recording in children suffering from neuromuscular diseases
Other: Muscular oximetry
6 minutes walking test performed in the routine medical care with muscle oximetry recording
- Muscular oxygenation [ Time Frame: 6 minutes ]Muscular oximetry
- 6 minutes walking distance [ Time Frame: 6 minutes ]6 minutes walking distance
- Motor function [ Time Frame: 25 minutes ]Motor function measure (MFM scale)
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03471676
|Contact: Emmanuelle LAGRUE, MD, PhD||+33 2 47 47 47 firstname.lastname@example.org|
|University Hospital, Tours||Recruiting|
|Tours, France, 37044|
|Contact: Emmanuelle LAGRUE, MD, PhD +33 2 47 47 47 57 email@example.com|
|Principal Investigator:||Emmanuelle LAGRUE, MD, PhD||University Hospital, Tours|