DNA Methylation and Hydroxymethylation Levels in Patients With Coronary Heart Disease
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT03462277|
Recruitment Status : Recruiting
First Posted : March 12, 2018
Last Update Posted : November 12, 2018
|Condition or disease|
|Coronary Heart Disease|
- To determine the levels of DNA methylation and hydroxymethylation with coronary heart disease.
- To investigate the relationship between DNA methylation and hydroxymethylation and the degree of coronary atherosclerosis.
|Study Type :||Observational [Patient Registry]|
|Estimated Enrollment :||200 participants|
|Target Follow-Up Duration:||1 Year|
|Official Title:||DNA Methylation and Hydroxymethylation Levels in Patients With Coronary Heart Disease|
|Actual Study Start Date :||January 1, 2018|
|Estimated Primary Completion Date :||December 1, 2018|
|Estimated Study Completion Date :||December 1, 2018|
Control group was defined as people with negative findings in coronary angiograms.
Coronary Heart Disease group
CHD patients was defined as at least one lesion in a coronary artery or branches in coronary angiograms.
- DNA Methylation and Hydroxymethylation Levels [ Time Frame: 1 month ]Collection of blood samples and measuring the samples by PCR and ELISA
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03462277
|Contact: Dongying Zhang, email@example.com|
|The First Affiliated Hospital of Chongqing Medical University||Recruiting|
|Contact: Dongying Zhang, doctor +8613608398395 firstname.lastname@example.org|
|Study Director:||Dongying Zhang, doctor||First Affiliated Hospital of Chongqing Medical University|
|Principal Investigator:||Dan Jiang||First Affiliated Hospital of Chongqing Medical University|