The Use of Perfusion CT Derived Parameters as Early Acute Pancreatitis Severity Biomarker Compared to Clinico Biological Score (K-PA)
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|ClinicalTrials.gov Identifier: NCT03456557|
Recruitment Status : Completed
First Posted : March 7, 2018
Last Update Posted : April 14, 2020
The investigators to establish whether early microvascular permeability parameter evaluated by perfusion-CT could be good biomarkers for severity in acute pancreatitis.
Therefore the investigators want to compare 48 hours-clinico-biological systemic inflammatory response syndrome score to initial microvascular permeability parameters ( ktrans - capillary membrane permeability factor- and pancreatic blood flow ) calculated by OLEA software using inclusion perfusion CT.
|Condition or disease||Intervention/treatment||Phase|
|Acute Pancreatitis||Radiation: Perfusion computed tomography.||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||15 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||The Use of Perfusion CT Derived Parameters as Early Acute Pancreatitis Severity Biomarker Compared to Clinico Biological Score|
|Actual Study Start Date :||March 7, 2018|
|Actual Primary Completion Date :||December 9, 2018|
|Actual Study Completion Date :||December 9, 2018|
|Experimental: Computed tomography.||
Radiation: Perfusion computed tomography.
Using specific post treatment imaging software ( Olea® ) we will calculatell permeability parameters : the pancreatic blood flow and the k-trans, capillary membrane permeability factor.
- Relation between CT perfusion calculated k-trans and clinicobiological SIRS score in early phase of acute pancreatitis. [ Time Frame: admission day ]
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Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03456557
|Chu de Poitiers|
|Poitiers, France, 86021|