CT Portography in Grading of Liver Cirrhosis
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|ClinicalTrials.gov Identifier: NCT03453580|
Recruitment Status : Not yet recruiting
First Posted : March 5, 2018
Last Update Posted : March 5, 2018
|Condition or disease||Intervention/treatment|
|CT Portography Grading of Liver Cirrhosis||Radiation: multislice computed tomography portography|
The occurrence and development of Esophageal variceal bleeding and hepatic encephalopathy are closely related with portal vein system diseases, such as collateral circulation of portal hypertension and portal vein thrombosis.
The prevention of Esophageal variceal bleeding and hepatic encephalopathy in hepatic cirrhosis has become a hot spot in clinical practice.
Three-dimensional reconstruction of images obtained by multi-slice spiral computed tomography portography (MSCTP) is clear, realistic, and accurate.
It can directly and quickly display all anatomical information of collateral portal vein system, and is recognized as a good method to display blood vessels
|Study Type :||Observational|
|Estimated Enrollment :||68 participants|
|Official Title:||Role of Multi Slice Computed Tomography Portography in Grading of Liver Cirrhosis|
|Estimated Study Start Date :||May 25, 2018|
|Estimated Primary Completion Date :||September 30, 2019|
|Estimated Study Completion Date :||October 30, 2019|
- Radiation: multislice computed tomography portography
- Grading of liver cirrhosis [ Time Frame: 15 min ]
Grade I: i)level 4-5 by portal development will achieved in intrahepatic portal vein imaging; ii) collateral circulation mainly open at esophageal gastric fundus vein, or one branch of para-umbilical vein or esophageal peripheral vein was open; iii) hepatic artery-portal vein fistula or portal vein embolus was not formed.
Grade II: i)level 3-4 by portal development will achieved in intrahepatic portal vein imaging; ii) in addition to opening of collateral circulation at esophageal gastric fundus vein, 2-3 branches of para-umbilical vein or esophageal peripheral vein open; iii) some hepatic artery-portal vein fistula or portal vein embolus not observed.
Grade lll: level 2-3 by portal development are achieved in intrahepatic portal vein imaging; ii) esophageal gastric fundus vein, para-umbilical vein or esophageal peripheral vein all open, iii) hepatic artery-portal vein fistula or portal vein embolus is formed.
Then we will do correlation with child -pugh score
- prediction of esophageal varices and hepatic encephalopathy [ Time Frame: 20 min ]measuring diameters of main portal vein,left gastric, splenic, intra hepatic right and left portal vein.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03453580
|Contact: Mostafa Hashem Mahmoud, firstname.lastname@example.org|
|Contact: Marwa Mohamed Samy Mohamed, email@example.com|