Multi-dimensional Investigations of Negative Emotions and Drug-resistant Auditory Verbal Hallucinations in Psychosis
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT03449407|
Recruitment Status : Recruiting
First Posted : February 28, 2018
Last Update Posted : February 5, 2019
|Condition or disease|
|Schizophrenia Spectrum and Other Psychotic Disorders Hallucinations, Auditory|
|Study Type :||Observational|
|Estimated Enrollment :||60 participants|
|Official Title:||Multi-dimensional Investigations of Negative Emotions and Drug-resistant Auditory Verbal Hallucinations in Psychosis|
|Actual Study Start Date :||January 2016|
|Estimated Primary Completion Date :||June 30, 2019|
|Estimated Study Completion Date :||December 31, 2019|
- Psychotic symptomatology as measured by Positive and Negative Syndrome Scale (PANSS), Scale of Assessment for Positive Symptoms (SAPS), and the Psychotic Symptom Rating Scales (PSYRATS) [ Time Frame: Baseline ]Positive and Negative Syndrome Scale (PANSS) is an interview-based assessment of the severity of symptoms associated with schizophrenia, including positive, negative, and general psychopathology. Scale of Assessment for Positive Symptoms (SAPS) is an interview-based scale of positive symptoms of schizophrenia. SAPS consists of four areas: hallucinations, delusions, bizarre behaviour and positive formal thought disorder. Each area includes ratings of specific symptoms and a global rating. The Psychotic Symptom Rating Scale (PSYRATS) is a 17-item semi-structured interview measuring the severity of multiple dimensions of auditory hallucinations and delusions, including conviction and duration.
- Depressive symptomatology as measured by Calgary Depression Scale (CDS) [ Time Frame: Baseline ]Calgary Depression Scale (CDS) is a nine-item structured interview scale that assesses depressive symptoms in patients with schizophrenia.
- Beliefs about voices as measured by Beliefs about Voices Questionnaire - Revised (BAVQ-R) [ Time Frame: Baseline ]BAVQ-R is a self-report questionnaire that consists of three subscales pertaining to beliefs about voices: malevolence (i.e. voices as evil and persecutory), benevolence (i.e. voices as helpful), and omnipotence (i.e. voices as controlling and powerful).
- Anxiety severity as measured by Beck anxiety inventory (BAI) [ Time Frame: 1 week ]BAI is a self-report questionnaire that measures anxiety severity and unique symptom features that are independent of that in depression, including somatic symptoms and subjective experience of panic and anxiety.
- Mood states as measured by Visual analogue scale (VAS) [ Time Frame: 1 week ]A simple visual analogue scale assessing state depression, state anxiety and state happiness will be conducted.
- Cognitive capacity as measured by the Wechsler Adult Intelligence Scale - IV (HK) short form (WAIS-IV) [ Time Frame: Baseline ]An instrument developed to assess cognitive ability and the relationship between intellectual functioning and memory of adults. The WAIS-IV (HK) short form includes four subscales - arithmetic, visual puzzle, information, and coding.
- Handedness as measured by Edinburgh Handedness Inventory (EHI) [ Time Frame: Baseline ]A self report questionnaire assessing the dominance of one's right or left hand in everyday activities.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03449407
|Contact: Suzanne Ho-wai So||(852)firstname.lastname@example.org|
|Chinese University of Hong Kong||Recruiting|
|Hong Kong, Hong Kong|
|Contact: Suzanne Ho-wai So (852)39436472 email@example.com|