Duchenne Muscular Dystrophy Heart Study (DMD-HS)
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT03443115|
Recruitment Status : Recruiting
First Posted : February 22, 2018
Last Update Posted : February 22, 2018
Retrospective cohort study including patients with genetically proven Duchenne muscular dystrophy, diagnosed from January 1993 to March 2020.
Inclusion of the data relative to genetic diagnosis, clinical characteristics at baseline, cardiac and respiratory workup, medical treatments (ACE inhibitors, steroids), surgical procedures, and occurrence during follow-up of cardiac, respiratory and fatal events.
Objectives are to describe long-term natural history of the disease, vital prognosis, genotype-phenotype correlations, effect of treatments.
|Condition or disease|
|Duchenne Muscular Dystrophy Duchenne Muscular Dystrophy-Associated Dilated Cardiomyopathy|
|Study Type :||Observational|
|Estimated Enrollment :||700 participants|
|Official Title:||Multicenter Cohort Study on Duchenne Muscular Dystrophy Cardiomyopathy|
|Actual Study Start Date :||June 27, 2017|
|Primary Completion Date :||February 16, 2018|
|Estimated Study Completion Date :||March 15, 2020|
- All-cause mortality [ Time Frame: Follow-up completed in March 2020 ]
- Hospitalization for heart failure [ Time Frame: Follow-up completed in March 2020 ]
- Dilated cardiomyopathy [ Time Frame: Follow-up completed in March 2020 ]
- Hospitalization for acute respiratory failure [ Time Frame: Follow-up completed in March 2020 ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03443115
|Contact: Karim Wahbi, MD, PhDemail@example.com|
|Cochin Reference Center for Neuromuscular Diseases||Recruiting|
|Paris, France, 75014|
|Contact: Karim Wahbi, MD, PhD +33158411653 firstname.lastname@example.org|