Late Potentials and Ablation Index in Ventricular Tachycardia Ablation
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|ClinicalTrials.gov Identifier: NCT03437408|
Recruitment Status : Recruiting
First Posted : February 19, 2018
Last Update Posted : August 13, 2019
|Condition or disease||Intervention/treatment||Phase|
|Ventricular Tachycardia||Device: Mapping and ablation||Not Applicable|
Show Detailed Description
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||15 participants|
|Intervention Model:||Single Group Assignment|
|Intervention Model Description:||Ventricular Substrate maps in patients undergoing ablation for VT - maps collected with automated tagging in different pacing modalities. Validation of collected substrate. Collection of impedance and ablation index data during ablation|
|Masking:||None (Open Label)|
|Official Title:||Influence of Ventricular Pacing on Automated Ventricular Substrate Mapping and Relationship Between Ablation Index and Impedance Drop in the Human Ventricle|
|Actual Study Start Date :||June 26, 2019|
|Estimated Primary Completion Date :||July 30, 2021|
|Estimated Study Completion Date :||July 30, 2021|
Experimental: Mapping and ablation
Automated Substrate maps with different pacing modes. Validation of collected substrate. Data collection during ablation
Device: Mapping and ablation
High density substrate map. Data collection during ablation
- Areas with ventricular tachycardia substrate [ Time Frame: Through study completion, an average of 1 year ]Quantification of late potential area and scar area with comparison between pacing modalities
- Relationship between ablation index and impedance drop [ Time Frame: Through study completion, an average of 1 year ]Quantification of the relationship between ablation index and impedance drop during ablation.
- Relationship between Force Time Integral and impedance drop [ Time Frame: Through study completion, an average of 1 year ]Quantification of the relationship between Force Time Integral and impedance drop during ablation.
- Relationship between electrogram attenuation and impedance drop [ Time Frame: Through study completion, an average of 1 year ]Quantification of the relationship between electrogram attenuation and impedance drop during ablation.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03437408
|Contact: Waqas Ullah, PhD||02380777222 ext firstname.lastname@example.org|
|Southampton General Hospital||Recruiting|
|Southampton, Hampshire, United Kingdom, SO16 6YD|
|Contact: Waqas Ullah email@example.com|
|Principal Investigator:||Waqas Ullah, PhD||University Hospital Southampton NHS Foundation Trust|