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Can Reverse Dieting Prevent Weight Regain After Weight Loss

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT03434431
Recruitment Status : Completed
First Posted : February 15, 2018
Last Update Posted : March 1, 2019
Information provided by (Responsible Party):
lilian de Jonge, George Mason University

Brief Summary:

Introduction: It is known that weight loss results in decreased Resting Energy Expenditure (REE), due to a decrease in lean body mass (LBM), but also due to metabolic adaptation, resulting in a higher energy efficiency, responsible for weight regain. Powerlifting athletes submit themselves to caloric restriction before a competition to reach their desired weight category. After cessation of the restrictive diet body mass will quickly return to pre-diet values with a disproportionate gain of fat mass. To avoid fat gain 'reversed dieting' has become popular among athletes. This involves increasing caloric intake in a stepwise fashion with the assumption that the small increases in caloric intake might help to restore energy expenditure toward pre-dieting levels and decrease the chance of increasing fat mass. While anecdotal reports of successful reverse dieting are available, research is needed to evaluate its true efficacy. In addition, if the method would work in non-athletes this could be an important change in the risk of weight regain after a weight loss diet. .

Aim: To test the effects of the reverse dieting protocol in the prevention of metabolic adaptation following a period of caloric restriction in weight training athletes. .

Methods: A convenience sample of 3 powerlifters is used in this study. They are submitted to a 750kcal/day caloric deficit with a protein intake set at 2x bodyweight (kg) and 30%en from fat for 6 weeks, adjusted weekly. The reverse dieting protocol adds 100kcal during week 1-4 and 150kcal during week 5-8. REE is measured bi-weekly and body composition at day 1 of caloric restriction and day 1 and day 56 of reverse dieting. Exercise is kept constant during the entire period. .

Condition or disease Intervention/treatment
Obesity Other: Reverse dieting

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Study Type : Observational
Actual Enrollment : 3 participants
Observational Model: Cohort
Time Perspective: Cross-Sectional
Official Title: Does Slow Reintroduction of Calories After Weight Loss Prevent Weight Regain in Trained Athletes? A Feasibility Study
Actual Study Start Date : July 17, 2016
Actual Primary Completion Date : October 27, 2016
Actual Study Completion Date : October 27, 2016

Resource links provided by the National Library of Medicine

Primary Outcome Measures :
  1. Metabolic adaptation [ Time Frame: July 2017-October 2017 ]
    energy expended per unit lean body mass

Information from the National Library of Medicine

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Ages Eligible for Study:   20 Years to 25 Years   (Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
a convenience sample of 3 male powerlifters

Inclusion Criteria:

  • member of the GMU powerlifting team

Exclusion Criteria:

  • no member of the GMU powerlifting team
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Responsible Party: lilian de Jonge, Assistant Professor, Nutrition and Food Studies, College of Health and Human Services, George Mason University Identifier: NCT03434431    
Other Study ID Numbers: 905083-2
First Posted: February 15, 2018    Key Record Dates
Last Update Posted: March 1, 2019
Last Verified: February 2019
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Keywords provided by lilian de Jonge, George Mason University:
metabolic adaptation
weight regain
reverse dieting
Additional relevant MeSH terms:
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Weight Loss
Body Weight Changes
Body Weight