Distribution of Non-Motor Symptoms in Idiopathic Parkinson's Disease and Secondary Parkinsonism
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ClinicalTrials.gov Identifier: NCT03432338 |
Recruitment Status :
Completed
First Posted : February 14, 2018
Last Update Posted : March 12, 2021
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BACKGROUND:
Non-Motor Symptoms (NMS) are frequent in patients with Idiopathic Parkinson's Disease (IPD). Clinical expressions, postulated pathophysiological mechanisms and responsiveness to antiparkinson medication represent differences between IPD and secondary Parkinsonism (SP).
OBJECTIVES:
To evaluate NMS expressions in IPD, SP and a control group.
METHODS:
Diagnosis of SP was supported by comorbidity, radiological findings, type of onset, onset rate and progression, exposures for neuroleptics, and responsiveness to pharmacological antiparkinson therapy.
The participants were consecutively recruited at two outdoor patient clinics. The Well-Being Map™ for evaluation. These were completed by the participants at one point before visit. The controls consisted of non-Parkinsonian individuals, matched by age and gender.
Condition or disease | Intervention/treatment |
---|---|
Parkinson Disease | Other: inquiries |

Study Type : | Observational |
Actual Enrollment : | 208 participants |
Observational Model: | Case-Control |
Time Perspective: | Cross-Sectional |
Official Title: | Distribution of Non-Motor Symptoms in Idiopathic Parkinson's Disease and Secondary Parkinsonism A Controlled, Descriptive Cross-sectional Study Using Parkinson's Well-Being Map™ |
Actual Study Start Date : | January 1, 2016 |
Actual Primary Completion Date : | December 31, 2016 |
Actual Study Completion Date : | July 31, 2017 |

Group/Cohort | Intervention/treatment |
---|---|
idiopathic parkinson
Classical Parkinson´s disease, idiopathic
|
Other: inquiries
Inquires reported to clinician. |
secondary parkinsonism
parkinsonism due to other reasons than idiopathic
|
Other: inquiries
Inquires reported to clinician. |
controls
persona matched by age and gender, non parkinsonism
|
Other: inquiries
Inquires reported to clinician. |
- Prevalence of selfreported motor and non-motor symptoms with The Parkinson´s Well-being map [ Time Frame: 12 months ]
A graded check list presented in The Parkinson´s Well-BeingMap is used in the registration of self reported frequencies and self experienced strength of Motor and Non- Motor Symptoms in two different forms of parkinsonism and in a group of healthy controls.The experienced magnitude of suffering is visualized in a spider diagram reflecting the strength of each item on an ordinal scale from 0 to four.
Primary outcome measure is to compare reported frequencies between groups.
- Prevalence of combinations of reported motor and non-motor symptoms using [ Time Frame: 12 months ]Secondary outcome measures are to study commonly reported combinations of non-motor symptoms within the groups, with respect to gender and duration of disease.

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Ages Eligible for Study: | 65 Years to 90 Years (Older Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | Yes |
Sampling Method: | Non-Probability Sample |
Inclusion Criteria:
" Clinical diagnosis of Idiopathic Parkinson´s Disease " Clinical diagnosos of secondary parkinsonism " Healthy controls " Age >65 years " >1 year duration of disease after diagnose
Exclusion Criteria:
" Participation in other studies " Severe disease of psychiatric origin " Severe cognitive impairment

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03432338
Study Director: | Boel Andersson Gäre, PhD | Region Jönköping County |
Responsible Party: | Örjan Skogar, MD,PhD, Region Jönköping County |
ClinicalTrials.gov Identifier: | NCT03432338 |
Other Study ID Numbers: |
Dnr 2016/118-31 |
First Posted: | February 14, 2018 Key Record Dates |
Last Update Posted: | March 12, 2021 |
Last Verified: | March 2021 |
Individual Participant Data (IPD) Sharing Statement: | |
Plan to Share IPD: | No |
Studies a U.S. FDA-regulated Drug Product: | No |
Studies a U.S. FDA-regulated Device Product: | No |
Parkinson Disease Parkinsonian Disorders Parkinson Disease, Secondary Basal Ganglia Diseases Brain Diseases |
Central Nervous System Diseases Nervous System Diseases Movement Disorders Synucleinopathies Neurodegenerative Diseases |