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Trial record 68 of 3333 for:    China Medicine University Hospital

High-flow Nasal Cannula Oxygen Therapy With the Chest Trauma Patients

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ClinicalTrials.gov Identifier: NCT03430258
Recruitment Status : Not yet recruiting
First Posted : February 12, 2018
Last Update Posted : February 12, 2018
Sponsor:
Information provided by (Responsible Party):
Second Affiliated Hospital, School of Medicine, Zhejiang University

Brief Summary:
This prospective randomized controlled study was conducted in the emergency intensive care units (EICU) of the second affiliated hospital Zhejiang university school of medicine, a large tertiary university hospital in HangZhou, China.The aim of this randomized study was to compare the effectiveness of high-flow nasal cannula with conventional oxygen therapy in ICU patients with blunt thoracic injury.

Condition or disease Intervention/treatment Phase
Blunt Thoracic Injury Lung Ultrasound Score Device: high-flow nasal cannula Device: Conventional oxygen therapy Not Applicable

Detailed Description:
This prospective randomized controlled study was conducted in the emergency intensive care units (EICU) of the second affiliated hospital Zhejiang university school of medicine, a large tertiary university hospital in HangZhou, China.The aim of this randomized study was to compare the effectiveness of high-flow nasal cannula with conventional oxygen therapy in ICU patients with blunt thoracic injury.

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Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 90 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: High-flow Nasal Cannula Oxygen Therapy With the Chest Trauma Patients
Estimated Study Start Date : March 1, 2018
Estimated Primary Completion Date : March 30, 2019
Estimated Study Completion Date : March 30, 2019

Resource links provided by the National Library of Medicine


Arm Intervention/treatment
Placebo Comparator: conventional oxygen therapy
oxygen was delivered by a nasal cannula or nonrebreather mask
Device: Conventional oxygen therapy
Conventional oxygen therapy

Active Comparator: High-flow Nasal Cannula Oxygen Therapy
High-flow Nasal Cannula Oxygen Therapy
Device: high-flow nasal cannula
high flow of air with supplemental oxygen was delivered by an Optiflow cannula interface using an AIRVO 2 blower humidifier




Primary Outcome Measures :
  1. compare the effectiveness of high-flow nasal cannula with conventional oxygen therapy in ICU patients with blunt thoracic injury. [ Time Frame: 72 hours ]
    High-flow nasal cannula could reduce the intube rate of patients with blunt thoracic injury,and improve the the lung aeration for patients with thoracic injury


Secondary Outcome Measures :
  1. number of days in ICU [ Time Frame: 7 days ]
    High-flow nasal cannula could reduce the number of days for the patients treatments in ICU



Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

- The trauma registry was used to identify patients with moderate to severe blunt thoracic injury (abbreviated injury scale (AIS) chest score ≥3) admitted to the ICU

Exclusion Criteria:

  1. had intubation and used the mechanical ventilation within 2 hours
  2. had the emergency surgerys within 2 hours
  3. patients can not accessed by transthoracic lung ultrasound because of the sever aerodermectasia or pneumothorax
  4. the Glasgow Coma Scale <8

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Responsible Party: Second Affiliated Hospital, School of Medicine, Zhejiang University
ClinicalTrials.gov Identifier: NCT03430258     History of Changes
Other Study ID Numbers: 19850703
First Posted: February 12, 2018    Key Record Dates
Last Update Posted: February 12, 2018
Last Verified: January 2018
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No

Additional relevant MeSH terms:
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Thoracic Injuries
Wounds and Injuries