Ultrasound Assessment of Changes in the Diameter of the Common Carotid Artery After Increasing the Preload of the Heart
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|ClinicalTrials.gov Identifier: NCT03412422|
Recruitment Status : Not yet recruiting
First Posted : January 26, 2018
Last Update Posted : March 20, 2019
|Condition or disease||Intervention/treatment|
|Critical Illness Fluid Responsiveness||Diagnostic Test: fluid responsiveness assessment|
|Study Type :||Observational|
|Estimated Enrollment :||40 participants|
|Official Title:||Ultrasound Assessment of Changes in the Diameter of the Common Carotid Artery After Increasing the Preload of the Heart With Passive Leg Raise and Intravenous Fluid Infusion|
|Estimated Study Start Date :||June 1, 2019|
|Estimated Primary Completion Date :||October 1, 2020|
|Estimated Study Completion Date :||October 1, 2020|
Acute circulatory failure
Mechanically ventilated patients with acute circulatory failure, monitored with PiCCO method, who need fluid responsiveness assessment.
Diagnostic Test: fluid responsiveness assessment
During the procedure, the investigator will be imaging one of the carotid arteries with ultrasound. In expiratory phase, four sets of three video loops will be recorded: before and after PLR and then before and after fluid challenge. There also will be noted hemodynamic parameters measured with PiCCO monitor. The fluid challenge is defined as administration of 500ml of crystalloid in less than 10 minutes. Later, another investigator, who will be blinded to other data, will measure the maximal and minimal diameter of CCA in each loop. The measurements will be averaged and eventually two values (maximal an minimal) from each set will be obtained.
- Changes in the diameter of the common carotid artery [ Time Frame: 1 minute after PLR test and 1 minute after fluid challenge ]The diameter will be measured with ultrasound
- Evaluation the value of changes in the diameter of CCA as the predictor of fluid responsiveness. [ Time Frame: 1 minute after PLR test and 1 minute after fluid challenge ]The changes in the diameter of CCA will be compared with the changes in cardiac output measured with PiCCO method.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03412422
|Contact: Maciej Piwodafirstname.lastname@example.org|
|Department of Anesthesiology and Intensive Care, Uniwersytecki Szpital Kliniczny w Opolu||Not yet recruiting|
|Opole, Opolskie, Poland, 45-372|
|Contact: Maciej Piwoda, MD 0048774520302 email@example.com|
|Contact: Ryszard Gawda, MD PhD|
|Sub-Investigator: Tomasz Czarnik, MD PhD|
|Sub-Investigator: Maciej Marszalski, MD|