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Trial record 4 of 663 for:    SMS

Use of SMS and Interactive Reminders to Improve Timely Immunization Coverage

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT03379467
Recruitment Status : Completed
First Posted : December 20, 2017
Last Update Posted : December 21, 2017
Sponsor:
Information provided by (Responsible Party):
Subhash Chandir, Interactive Research and Development

Brief Summary:

Pakistan has one of the highest infant mortality rates in the world. One child in eleven dies before their fifth birthday. In part, this is due to the low coverage rate of routine childhood immunizations. Since Pakistan is a Low Middle Income Country (LMIC) it is essential that an immunization intervention be developed that is suitable for its socioeconomic setting. The tele-density of Pakistan exceeds 70% and the cost of SMS in Pakistan is very low. Moreover the use of SMS in the country has broadened beyond the conventional use of peer-peer chat to include social networking, SMS banking, delivery tracking, advertising, business, disaster management, and identity verification. This study will utilise this prevalence of mobile phones to assess whether simple and interactive sms reminders can serve to increase childhood immunization coverage and timeliness.

The pilot study will be carried out only in 2 EPI (Extended program on Immunization) centers at Korangi. The pilot will determine whether automated text messages produce increased immunization coverage in the reminder groups compared to the control group. 656 participants will be enrolled at Penta-1 and will be followed up until measles-2 vaccination. The results of proposed pilot will provide the basis for a large scale-up study in urban and rural settings in Pakistan.


Condition or disease Intervention/treatment Phase
Immunization; Infection SMS Other: SMS Reminder Other: Interactive Reminder Not Applicable

  Show Detailed Description

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 655 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Intervention Model Description: This is an individually randomized, three-arm parallel group design randomized control trial with equal allocation in the two treatment groups and control group. The parents of infants in SMS and interactive reminder groups will receive 3-5 reminders for scheduled follow-up immunization visits. The difference in between SMS and interactive reminders is that parents in SMS reminders are not asked to respond back to SMS reminders. The infants in control group will carry out routine follow-ups without any added intervention.
Masking: None (Open Label)
Masking Description: The allocation sequence will be concealed from the study staff responsible for screening and enrolling participants in serially numbered, opaque, sealed envelopes.
Primary Purpose: Health Services Research
Official Title: Use of SMS and Interactive Reminders to Improve Timely Immunization Coverage: A Randomized Controlled Trial
Actual Study Start Date : May 23, 2011
Actual Primary Completion Date : March 8, 2014
Actual Study Completion Date : March 8, 2014

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Measles

Arm Intervention/treatment
Experimental: SMS Reminder

Single SMS at each of the following times:

  • 3 days before immunization
  • 1 day before immunization
  • Day of immunization
Other: SMS Reminder
A text message sent as a reminder for immunization on the registered phone number

Experimental: Interactive Reminder

Single SMS at each of the following times:

  • 3 days before immunization
  • 1 day before immunization
  • Day of immunization On the day of immunization, study participants are required to respond back through SMS notifying us that child got vaccinated or if not, the reason for delay in immunization. In case of no response, 2 additional reminders will be sent at:
  • 1 day after scheduled immunization date
  • 1 week after scheduled immunization date
Other: Interactive Reminder
A text message sent as a reminder for immunization on the registered phone number which requires the receiver to respond back

No Intervention: Control
Subjects in this arm will not receive any intervention



Primary Outcome Measures :
  1. Measles - 2 Completion [ Time Frame: When the participants reach 2 years of age ]
    The primary outcome for the study is the proportion of infants completing measles 2 vaccine on schedule.



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Ages Eligible for Study:   6 Weeks to 12 Weeks   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Child presenting for pentavalent 1- vaccine
  • Caregivers who owned a cellphone or had access to one
  • Caregivers permanently residing in Korangi Town, Karachi

Exclusion Criteria:

  • Child presenting for a vaccine other than pentavalent -1
  • Caregivers not having access to a cell phone
  • Caregivers residing outside of Korangi or planning to move from the catchment area

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03379467


Sponsors and Collaborators
Interactive Research and Development
Investigators
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Principal Investigator: Subhash Chandir, Phd Interactive Research and Development (IRD)

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Responsible Party: Subhash Chandir, Primary Investigator, Interactive Research and Development
ClinicalTrials.gov Identifier: NCT03379467     History of Changes
Other Study ID Numbers: IRD_IRB_2011_05_005
First Posted: December 20, 2017    Key Record Dates
Last Update Posted: December 21, 2017
Last Verified: December 2017
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Keywords provided by Subhash Chandir, Interactive Research and Development:
SMS Reminder
Two-way Reminder
Additional relevant MeSH terms:
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Vaccines
Immunologic Factors
Physiological Effects of Drugs