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Novel Equation for Estimating Resting Energy Expenditure

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ClinicalTrials.gov Identifier: NCT03377413
Recruitment Status : Recruiting
First Posted : December 19, 2017
Last Update Posted : December 20, 2017
Sponsor:
Information provided by (Responsible Party):
Dong Jie, Peking University First Hospital

Brief Summary:
The energy and nutrition states are closely associated with CKD patients complications and outcomes.To reach the energy balance target, we need the accurate resting energy expenditure level of patients. Traditional equations are not applicable to CKD patients,so we aim to develop and validate a equation for estimating resting energy expenditure in CKD patients.

Condition or disease
Resting Energy Expenditure Chronic Kidney Disease

Study Type : Observational
Estimated Enrollment : 400 participants
Observational Model: Case-Only
Time Perspective: Cross-Sectional
Official Title: Novel Equation for Estimating Resting Energy(REE) Expenditure in Chronic Kidney Disease(CKD) 3-5 Stages Patients
Actual Study Start Date : September 1, 2017
Estimated Primary Completion Date : March 30, 2019
Estimated Study Completion Date : September 1, 2019

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Kidney Diseases




Primary Outcome Measures :
  1. Novel equation development [ Time Frame: September 1, 2017 to June 1, 2018 ]
    Developed equation for estimating REE in CKD 3-5 stages patients

  2. Novel equation validation [ Time Frame: June 1, 2018 to March 1, 2019 ]
    Validate the noval equation with REE obtained by indirect calorimetry (IC).



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Ages Eligible for Study:   18 Years to 80 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
chronic kidney disease 3-5 stages
Criteria

Inclusion Criteria:

  • CKD 3-5 stages
  • Age:18-80 years old

Exclusion Criteria:

  • Dialysis and kidney transplantation;
  • Acute complications to hospitalization
  • 1 month prior to the study;
  • Acute or chronic infections, cancer and other wasting diseases in the past year;
  • Thyroid dysfunction;
  • Acute onset of podagra; Musculoskeletal diseases;
  • Respiratory diseases (asthma, pleural effusion, pneumothorax, COPD);
  • History of hormonal drugs use;
  • During pregnancy or lactation

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03377413


Contacts
Contact: Xiao Xu 010-83572497 xuxiaoqd@126.com

Locations
China, Beijing
Renal Division and Institute of Nephrology, Peking University First Hospital Recruiting
Beijing, Beijing, China, 100034
Contact: Jie Dong, MD    086-010-83572388    dongjie@bjmu.edu.cn   
Sponsors and Collaborators
Peking University First Hospital
Investigators
Study Director: Jie Dong Renal Division and Institute of Nephrology, Peking University First Hospital

Responsible Party: Dong Jie, Clinical Professor in Renal Division, Department of Medicine, Peking University First Hospital
ClinicalTrials.gov Identifier: NCT03377413     History of Changes
Other Study ID Numbers: REE equation
First Posted: December 19, 2017    Key Record Dates
Last Update Posted: December 20, 2017
Last Verified: December 2017

Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No

Additional relevant MeSH terms:
Kidney Diseases
Renal Insufficiency, Chronic
Urologic Diseases
Renal Insufficiency