Cognitive Effects of Citicoline in Men and Women With Age-Associated Memory Impairment
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This study is a 12-week, randomized, double-blind, placebo-controlled trial of citicoline in healthy men and women with Age-Associated Memory Impairment. Cognitive assessments will be performed to determine whether citicoline administration with supportive memory, compared to placebo administration.
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Layout table for eligibility information
Ages Eligible for Study:
50 Years to 85 Years (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
male or female, 50-85 years of age
at least a high school diploma or the equivalent
self-reported memory loss
scores ≥24 on the Mini-Mental State Examination, ≥85 on the Kaufman Brief Intelligence Test, Second Edition, ≤5 on the Geriatric Depression Scale, and 4, 3, or 2 on the Spatial Span Test
no health conditions that would prevent him or her from fulfilling the study requirements on the basis of medical history and routine laboratory test results
abnormal laboratory test results
major medical or neurological illness
female who is pregnant, planning to be pregnant during the study period
requiring treatment with a drug which might obscure the action of the study treatment