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Prevalence of Oral Manifestations of Iron Deficiency Anemia in Egyptian Population

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ClinicalTrials.gov Identifier: NCT03365570
Recruitment Status : Not yet recruiting
First Posted : December 7, 2017
Last Update Posted : December 7, 2017
Sponsor:
Information provided by (Responsible Party):
Eman Mohamed Abdallah Alsheikh, Cairo University

Brief Summary:
According to WHO Report (2002), iron deficiency anemia was considered to be the most important contributing factor to the global burden of anemia. Children and women in reproductive ages are more at risk factor for developing iron deficiency anemia (Suneeta, 2007).No previous study has been held to assess prevalence of oral manifestations of iron deficiency anemia as a hospital-based cross-sectional study on a sample of Egyptian patients in hematology department (no previous data recorded).

Condition or disease
Oral Disease , Iron Deficiency Anemia

Detailed Description:
Study Design: An observational (cross-sectional study) .Patients diagnosed with Iron deficiency anemia that attending at the Hematology department at El Qasr Al-Einy Cairo University Hospital will be enrolled in the study. The data collected through a questionnaire taken through an interview between the investigator and the patient.Clinical examination performed for oral mucosa, the duration of symptoms and type of lesions will be recorded. Patients' age, sex, duration of illness, type of anemia, location of any oral lesion or abnormality, history of drug and alcohol consumption, and presence or absence of dentures, will be recorded. All participants will be asked to sign a study-related informed consent. Oral manifestations of these patients will be evaluated by an oral medicine master student (the investigator).Patients diagnosed with iron deficiency anemia based on their blood tests ,All ages of Males and females will be included. But Patients suffering from any other systemic diseases known to influence oral and maxillofacial manifestations will be excluded.and Patients on drug therapy that may have oral mucosal manifestations also will be excluded.

Study Type : Observational
Estimated Enrollment : 400 participants
Observational Model: Ecologic or Community
Time Perspective: Cross-Sectional
Official Title: Prevalence of Oral Manifestations of Iron Deficiency Anemia in Egyptian Population: a Hospital Based Cross Sectional Study
Estimated Study Start Date : December 2017
Estimated Primary Completion Date : March 2018
Estimated Study Completion Date : July 2018

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Anemia Iron




Primary Outcome Measures :
  1. Prevalence of oral mucosal lesions [ Time Frame: 15 minutes ]
    Presence of oral mucosal lesions will be assessed by clinical picture into dichotomous outcome (Yes/No)


Secondary Outcome Measures :
  1. Oral health related quality of life (OHR-QoL) [ Time Frame: 15 minutes ]
    assessed by Chronic Oral Mucosal Diseases Questionnaire



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Ages Eligible for Study:   up to 70 Years   (Child, Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Patients diagnosed with Iron deficiency anemia that attending at the Hematology department at El Qasr Al-Einy Cairo University Hospital will be enrolled in the study. The data collected through a questionnaire taken through an interview between the investigator and the patient. Clinical examination performed for oral mucosa, the duration of symptoms and type of lesions will be recorded. Patients' age, sex, duration of illness, type of anemia, location of any oral lesion or abnormality, history of drug and alcohol consumption, and presence or absence of dentures, will be recorded. All participants will be asked to sign a study-related informed consent. Oral manifestations of these patients will be evaluated by an oral medicine master student (the investigator).
Criteria

Inclusion Criteria:

  • Patients diagnosed with iron deficiency anemia based on their blood tests.
  • All ages are will be included.
  • Males and females will be included.

Exclusion Criteria:

  • Patients suffering from any other systemic diseases known to influence oral and maxillofacial manifestations will be excluded.
  • Patients on drug therapy that may have oral mucosal manifestations.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03365570


Contacts
Contact: Eman Mohamed Alsheikh, BDS 00201127006229 emanalsheikh7@gmail.com
Contact: Eman Mohamed Amr, Associate Professor

Locations
Egypt
Cairo University Recruiting
Cairo, Egypt, 12613
Contact: Eman Alsheikh, BDS         
Contact: Eman Amr, associate proffessor         
Sponsors and Collaborators
Cairo University
Investigators
Study Chair: Fatheya Zahran, Professor Head of the Department of Oral Medicine and periodontology Cairo University

Publications of Results:
Other Publications:
Responsible Party: Eman Mohamed Abdallah Alsheikh, BDS, Master student at oral medicine department, Cairo University
ClinicalTrials.gov Identifier: NCT03365570     History of Changes
Other Study ID Numbers: oral cavity and anemia
First Posted: December 7, 2017    Key Record Dates
Last Update Posted: December 7, 2017
Last Verified: December 2017
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: Undecided

Keywords provided by Eman Mohamed Abdallah Alsheikh, Cairo University:
hemoglobin, iron, oral lesions, oral manifestations,cross-sectional study

Additional relevant MeSH terms:
Anemia, Iron-Deficiency
Anemia
Deficiency Diseases
Oral Manifestations
Mouth Diseases
Hematologic Diseases
Anemia, Hypochromic
Iron Metabolism Disorders
Metabolic Diseases
Malnutrition
Nutrition Disorders
Stomatognathic Diseases
Signs and Symptoms