Correlation of Two Methods for Cough Peak Flow Measurement in Intubated Patients (COUGH-ICU)
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT03357198|
Recruitment Status : Completed
First Posted : November 29, 2017
Last Update Posted : January 31, 2019
Cough Peak Flow (CPF) seems to be an efficient tool to assess cough capacity for the intensive care unit (ICU) ventilated patient. CPF can be used in the ventilator weaning process, as reflecting the upper airways protection capacity.
CPF requires disconnection of the patient from the ICU ventilator, supplemental material (handheld spirometer, antibacterial filter) and an excellent synchronization between the specialized caregiver and the patient.
We aimed that CPF with the ventilator built-in flow-meter is correlated with CPF using a handheld flowmeter connected to the endotracheal tube.
|Condition or disease|
|Respiratory Insufficiency Ventilator Weaning|
|Study Type :||Observational|
|Actual Enrollment :||62 participants|
|Official Title:||Correlation of Cough Peak Flow Measurement by an Electronic Handheld Spirometer Connected to the Endotracheal Tube and by the Intensive Care Unit Ventilator Flowmeter.|
|Actual Study Start Date :||December 8, 2017|
|Actual Primary Completion Date :||August 29, 2018|
|Actual Study Completion Date :||August 29, 2018|
cough peak flow measurement
All enrolled patients will undergo measurement of cough peak flow by two methods, i.e. using a handheld electronic spirometer, and using the ventilator flowmeter, in a randomized order.
- Correlation coefficient for the two CPF assessment methods, on extubation day [ Time Frame: Within 1 hour before mechanical ventilation termination (extubation) ]Correlation coefficient for the two CPF assessment methods, on extubation day
- Discriminatory power of CPF to predict successful weaning of mechanical ventilation, i.e. no reintubation within 72 hours after extubation, or unsuccessful weaning. [ Time Frame: During the mechanical ventilation until 72 hours post extubation ]Thresholds of CPF will be tested as predictors of weaning success
- Assess the correlation between CPF and length of mechanical ventilation [ Time Frame: During the mechanical ventilation until 72 hours post extubation ]Assess the correlation between CPF and length of mechanical ventilation
- 3. Correlation between the two CPF assessment methods the days before extubation [ Time Frame: During the mechanical ventilation until 72 hours post extubation ]3. Correlation between the two CPF assessment methods the days before extubation
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03357198
|Orléans, France, 45000|
|Principal Investigator:||Guillaume FOSSAT||CHR Orléans|