Premedication Dyclonine Improves Visibility During Bowel Cleansing for Colonoscopy
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|ClinicalTrials.gov Identifier: NCT03352700|
Recruitment Status : Not yet recruiting
First Posted : November 24, 2017
Last Update Posted : November 24, 2017
|Condition or disease||Intervention/treatment||Phase|
|Bowel Preparation Scale the Amount of Air Bubble Adenoma Detection Rate||Drug: 3L PEG Drug: 3L PEG+Dyclonine Hydrochloride Mucilage||Phase 4|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||580 participants|
|Intervention Model:||Parallel Assignment|
|Official Title:||Premedication Dyclonine Improves Visibility During Bowel Cleansing for Colonoscopy|
|Estimated Study Start Date :||December 1, 2017|
|Estimated Primary Completion Date :||January 1, 2018|
|Estimated Study Completion Date :||February 1, 2018|
Placebo Comparator: 3L PEG
only used 3L PEG
Drug: 3L PEG
Group A patients (n = 300) used only 3L PEG before colonoscopy.
Experimental: 3L PEG+Dyclonine Hydrochloride Mucilage
used 3L PEG+Dyclonine Hydrochloride Mucilage
Drug: 3L PEG+Dyclonine Hydrochloride Mucilage
Patients in group B (n = 300) were additionally advised to Dyclonine Hydrochloride Mucilage plus 3 L PEG
- the amount of air bubbles [ Time Frame: 2 days ]The amount of intraluminal air bubbles was classified into four grades as shown below: Grade 0 = No or minimal scattered bubbles; Grade 1 = Bubbles covering at least half the luminal diameter; Grade 2 = Bubbles covering the circumference of the lumen; Grade 3 = Bubbles filling the entire lumen. Bubbles filling the entire lumen.
- adenoma detection rate [ Time Frame: 2 days ]The secondary end point of the study included adenoma detection rate
- mean total adenomas detected beyond first [ Time Frame: 2 days ]It was a new metric called ADR-Plus, the mean number of incremental adenomas after the fist.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03352700
|Contact: Zhaosheng Li, MDemail@example.com|
|Contact: Yu Baifirstname.lastname@example.org|
|Changhai Hospital, Second Military Medical University|
|Shanghai, China, 200433|
|Principal Investigator:||Peng Cheng||Xinhua Hospital, Shanghai Jiao Tong University School of Medicine|