Cardiovascular Risk Markers in Spinal Cord Injured Subjects of the Wheelchair Dancer Study
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|ClinicalTrials.gov Identifier: NCT03352505|
Recruitment Status : Recruiting
First Posted : November 24, 2017
Last Update Posted : August 30, 2019
The present study will analyze if exercise is able to elicit the well-known anti-atherogenic effects in patients with SCI. This will be evaluated by measuring vascular parameters such as endothelial and inflammatory blood markers, echocardiography of the heart and peripheral vessels, as well as blood pressure and arterial stiffness, in subjects performing either wheelchair dancing, wheelchair marathon or no sports. Further, it will be investigated, whether there is an association between neuroplasticity and cardiovascular health, as measured by electroencephalography (EEG), transcranial magnetic stimulation (TMS) and blood levels of the brain-derived neurotrophic factor (BDNF).
We hypothesize that the cardiovascular, physical and psychological benefits of wheelchair dancing and/or wheelchair marathon parallel improved neuroplasticity in SCI-patients
|Condition or disease|
|SCI - Spinal Cord Injury Cardiovascular Risk Factor|
|Study Type :||Observational|
|Estimated Enrollment :||50 participants|
|Official Title:||Associations Between the Cardiovascular Risk Markers and Neuroplasticity in Sedentary or Physically Active Spinal Cord Injured Subjects of the Wheelchair Dancer Study|
|Actual Study Start Date :||October 1, 2017|
|Estimated Primary Completion Date :||October 2019|
|Estimated Study Completion Date :||February 2020|
healthy walking control participants
wheelchair users, who are performing wheelchair dancing
wheelchair marathon participants
wheelchair users, who are participants in wheelchair/ handbike Marathon competitions
sedentary wheelchair patients
wheelchair users, who conduct exercise bouts less than 2 times per month
- comparison of cardiovascular risk factors between different study groups [ Time Frame: October 2017- June 2018 ]measurement for arterial stiffness parameters, via pulse wave analysis. Comparison between healthy individuals and patients using wheelchairs (three different groups).
- Evaluation of echocardiography results between different study groups [ Time Frame: October 2017- June 2018 ]Evaluation of echocardiography comparing healthy individuals and patients using wheelchairs (three different groups).
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03352505
|Contact: Josef Niebauer, Prof||+43(0) 5 firstname.lastname@example.org|
|Department of Neurology, Christian Doppler Klinik, Paracelsus Medical University Salzburg||Recruiting|
|Salzburg, Austria, 5020|
|Contact: Vanessa Frey, MSc 004357255-56812 email@example.com|
|Department of Sports Medicine, Prevention and Rehabilitation Paracelsus Medical University||Recruiting|
|Salzburg, Austria, 5020|
|Contact: Prof. Josef Niebauer, MD, PhD, MBA 00435725523200 ext 4270 firstname.lastname@example.org|