Healthful Diets and Risk of Hearing Loss
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|ClinicalTrials.gov Identifier: NCT03351023|
Recruitment Status : Completed
First Posted : November 22, 2017
Last Update Posted : November 22, 2017
|Condition or disease||Intervention/treatment|
|Hearing Loss||Other: no intervention-this was an observational study|
|Study Type :||Observational|
|Actual Enrollment :||70966 participants|
|Official Title:||Healthful Dietary Patterns and Risk of Hearing Loss in Women|
|Actual Study Start Date :||July 1, 1991|
|Actual Primary Completion Date :||June 30, 2013|
|Actual Study Completion Date :||June 30, 2013|
Nurses' Health Study II
Nurses' Health Study II, an ongoing cohort study of 116,430 female registered nurses in the US, aged 25-42 at enrollment in 1989. Participants have been followed by biennial mailed questionnaires that elicit updated information on diet, lifestyle, and various health outcomes; the follow-up rate over 26 years exceeds 90% of the eligible person-time.
Other: no intervention-this was an observational study
- Hearing loss [ Time Frame: 1991-2013 ]The primary outcome, self-reported hearing loss that was moderate or worse in severity, was determined based on responses to the 2009 and 2013 questionnaires on which participants were asked about their hearing. On the 2009 main questionnaire, participants were asked, "Do you have a hearing problem?" (no, mild, moderate, severe), and "At what age did you first notice a change in your hearing?" On the 2013 main questionnaire, participants were asked, "Which best describes your hearing?" (excellent, good, a little hearing trouble, moderate hearing trouble, deaf), and "Have you noticed a change in your hearing?" and, if the response was "Yes," "At what age did you first notice a change in your hearing?"
- hearing loss in HSSQ [ Time Frame: 1991-2013 ]Detailed hearing-related information was collected electronically in 2012 supplemental questionnaire from a representative subcohort of NHS II participants (n= 33,102) with and without reported hearing problems, including information on previous evaluation for hearing loss, laterality (unilateral or bilateral), and identified causes of hearing loss (e.g. ototoxic medications, ear trauma, otosclerosis, cholesteatoma, Meniere's disease, chronic ear infection). Data from the HSSQ were used to conduct sensitivity analyses using more refined case definitions (e.g. excluding known etiologies and unilateral hearing loss).
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03351023
|Principal Investigator:||Gary Curhan, MD, ScD||Brigham and Women's Hospital/Harvard Medical School|