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The purpose of this research study is to test an experimental procedure called intra-arterial delivery of verapamil in patients diagnosed with acute ischemic stroke. This study investigates the safety of intra-arterial delivery of verapamil, a drug used to treat vasospasm (spasm of a blood vessel), and how it affects recovery from stroke. Recruitment is limited to patients that have received mechanical thrombectomy as standard of care.
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Layout table for eligibility information
Ages Eligible for Study:
18 Years to 80 Years (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Written informed consent
18 years of age and over
Acute onset focal neurologic deficit consistent with acute ischemic stroke, or computed tomographic scan consistent with acute cerebral ischemia
Candidate for mechanical thrombectomy procedure
Onset of symptoms less than 8 hours
Measurable neurologic deficit (NIHSS >1)
Willingness to follow up with rehabilitation therapy
Anticipated life expectancy of at least 3 months
Pregnancy or suspected pregnancy (pregnancy test will be done on women of child-bearing potential)